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White House Counselor Kellyanne Conway (R) talks to U.S. Sen. Ted Cruz (R-TX) (L) prior to a swearing-in ceremony in the Vice President's ceremonial office at Eisenhower Executive Office Building March 2, 2017 in Washington, DC. (Alex Wong/Getty Images)

Texas Senator Ted Cruz can't catch a break when it comes to hugs. Actress Alyssa Milano curtly disinvited the Texas Senator on Twitter Thursday after the Senator responded: "we all need a hug" to her post "~GROUPHUG~ get in" from Tuesday.

Milano, an outspoken celebrity activist, had originally sent the tweet after Democratic candidate Jon Ossoff lost his bid for the congressional seat in Georgia's Sixth District.

"Not you, @tedcruz," Milano tweeted in response to Cruz on Thursday. "You're not invited."

Milano is known for her roles in movies like "Who's the Boss?," "Melrose Place" and "Charmed," and has unabashedly used her Twitter account to openly support liberal leaning candidates.

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This is not the first time that Cruz has had difficulty with public embraces or intimacy. Cruz punched and elbowed his wife Heidi in the face when the family had a group hug on stage after the Texas Senator announced he was suspending his run for president.

Not only does Cruz have difficulty hugging family members, he also has trouble kissing them as well. On the campaign trail in Iowa, the Senator attempted awkwardly to kiss his seven-year-old daughter Caroline next to the campaign bus, and his daughter reacted by flicking his face and pulling away.

Following Milano's rejection for Cruz's hug, Twitter mercilessly made fun of the Republican representatives, particularly how creepy it was that Cruz used a winky emoji in his response and drudged up some of the stories from the campaign.

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The back and forth between Milano and Cruz comes on the same day that the Senator issued his own rejection. Cruz joined Republican Senators Mike Lee, Ron Johnson and Rand Paul in rejecting the unpopular health care bill proposed by leaders of his party.

"Currently, for a variety of reasons, we are not ready to vote for this bill, but we are open to negotiation and obtaining more information before it is brought to the floor," the statement read.

"There are provisions in this draft that represent an improvement to our current health care system but it does not appear this draft as written will accomplish the most important promise that we made to Americans: to repeal Obamacare and lower their health care costs."

The detraction from Cruz and the other Republican Senators brings the whip count below the required 50 count majority needed in order to pass the legislation through the Senate.