Premarket Movers: Intel, Dow stocks lead gainers

Leading chip maker Intel Corp. moved higher after delivering upbeat first-quarter sales and a positive 2008 forecast that surprised analysts. Intel shares gained 8.2 percent to $22.63.

JPMorgan Chase & Co., the nation's third-biggest bank, reported profit fell 50 percent because of tight credit markets, but still beat analysts' predictions. Shares added 73 cents to $42.85.

And the world's largest beverage company, The Coca-Cola Co., said acquisitions, growth in its key carbonated beverage brands and success overseas helped boost its first-quarter profit by 19 percent on a 21 percent increase in sales, beating expectations. Shares added $1.01 to $60.95 in early action.

Shares of drug maker Pozen Inc. soared in premarket trading Wednesday following regulatory approval of its long-delayed migraine drug Treximet.

The Food and Drug Administration on Tuesday approved the drug, a combination of an anti-inflammatory drug and GlaxoSmithKline PLC's Imitrex, which is expected to begin competing against generics later this year.

Pozen shares rose 40.5 percent to $14.80 in early trading.

On the losing side, shares of Merrill Lynch & Co. fell 14 cents to $43.20. The Wall Street Journal reported the investment bank is set to write down an additional $6 billion to $8 billion in troubled assets as the U.S. mortgage and credit markets continue to deteriorate.