In Brazil, the Bovespa index was closed due to a public holiday in Sao Paulo and Rio de Janeiro.
Vale (NYSE:RIO), (SAO:VALE3), the world's largest iron-producer, lost as much as 4.4 percent to $9.58 after JPMorgan Chase & Co. cut its forecast for iron-ore prices in 2009 by 30 percent.
Meanwhile, Petrobras (NYSE:PZE), (SAO:PETR3) fell 3.4 percent to $4.90 after crude oil fell below $50 a barrel for the first time in almost two years.
Crude-oil futures fell for a fifth session, briefly plunging more than 7% to below $50 a barrel for the first time in almost two years, as global stocks tumbled and economic worries deepened.
Concerns that a slowing global economy will erode demand for fuel and raw materials pushed down commodity prices.
Vale and Petrobras are Brazil's two-biggest stocks.