Sheen, star of the television series "Two and a Half Men," is seeking help after a violent argument on Christmas Day.
The 44 year-old actor is following his wife, Brooke Mueller, who started attending a Los Angeles based clinic just days earlier.
"As a preventative measure, Charlie Sheen has entered a rehabilitation facility. He will take some time off from his series 'Two and a Half Men.' He has asked that his privacy be honored. No further statements are planned," publicist Stan Rosenfield said in a statement on Tuesday.
The actor was charged earlier this month with assaulting and threatening Mueller on December 25 during a family vacation in in Aspen, Colorado.
Mueller called police and told them Sheen had pulled a knife on her and threatened to have her killed when she said she would divorce him.
CBS said they "support Charlie Sheen in his decision today to begin voluntary in-patient care at a treatment center. We wish him nothing but the best as he deals with this personal matter."