When and Where: Birmingham v Chelsea kicks-off from St Andrews at 2.45 p.m. ET. The match will be shown on Fox Soccer Channel and online at FoxSoccer2Go. In the U.K., the match will be shown live on ITV1, so you can also catch a live stream through ITV1.com.

Preview: Chelsea begin life under caretaker manager Roberto Di Matteo with a tricky FA Cup fifth-round replay away at Championship side Birmingham City. Following Andre Villas-Boas' sacking over the weekend, all the attention will focus on how Chelsea's players react to the change in the managerial hot seat.

For Birmingham, it is hard to know whether they will be buoyed by the upheaval at Stamford Bridge or if they would have relished the chance to potentially put the final nail in Villas-Boas's Chelsea coffin.

While it can generally expected that there will be a positive reaction to a managerial change, things may well not be so clear-cut at Chelsea given Di Matteo's association with Villas-Boas and the large role that the players reportedly played in the Portuguese manager's downfall.

In naming his first team, Di Matteo is expected to rest a number of first-team players--including Didier Drogba, Ashley Cole, Michael Essien and Juan Mata. It's also anticipated that Fernando Torres will get yet another chance to rediscover his former glories up front.

Birmingham, currently sitting in sixth place in the Championship, will have a host of players unavailable for the visit of Chelsea. On-loan pair Andros Townsend and Erik Huseklepp are cup-tied, while recent arrivals Caleb Folan and Peter Ramage are also ineligible.

On the injury front Chris Hughton's side will also be missing defenders Stephen Carr, Steve Caldwell and David Murphy. Midfielder Keith Fahey is also set to miss out, while Curtis Davies is doubtful due to illness.

Prediction: Don't expect this to be a stroll in the park for Chelsea, but, with Birmingham missing so many first-team players, the Premier League outfit should just have enough to reach the last eight. Birmingham 1-2 Chelsea