Why is everyone making such a big deal out of Reese Witherspoon’s arrest? That’s what late night talk show host Chelsea Handler is wondering after her friend was arrested in Atlanta Friday for disorderly conduct.

The E News talk show host was arrested herself for driving under the influence when she was 21, and can’t understand why everyone is making such a fuss over her pal’s run-in with the law.

At the New York City premiere for the movie “Mud” on Monday, Handler told Entertainment Tonight the 37-year-old “Legally Blonde” star, whose full name is Laura Jeanne Resse Witherspoon, is doing just fine.

“She's doing fine. She's doing fine, you know?" Handler, 38, said of her friend, who is in “Mud” along with Matthew McConaughey. "She was just trying to protect her husband, so ... I mean everybody makes mistakes, so it's not a big deal."

Witherspoon’s husband, Jim Toth, was pulled over by authorities early Friday morning after his Ford Focus failed to stay within its lane. When police tried to conduct a sobriety test on the 42-year-old talent agent and sometime actor, Witherspoon popped out of the car, refusing to get back in the vehicle. She even asked the arresting officer if he knew who she was, as if her celebrity would help get Toth out of his arrest. Instead they both wound up in handcuffs.

Witherspoon has canceled interviews for “Mud,” a movie that is set to hit theaters April 26.

Witherspoon later apologized through her rep for her behavior in Atlanta. "Out of respect for the ongoing legal situation, I cannot comment on everything that is being reported right now. But I do want to say, I clearly had one drink too many and I am deeply embarrassed about the things I said," she told Us Weekly in a statement. "It was definitely a scary situation and I was frightened for my husband, but that is no excuse."

"I was disrespectful to the officer who was just doing his job," the statement continued. "The words I used that night definitely do not reflect who I am. I have nothing but respect for the police and I'm very sorry for my behavior."