College Football 2017 Week 6 Lines: Betting Odds For Top 25 Games

Sam Darnold USC — USC is the biggest betting favorite in Week 6 of the college football season. Pictured: Sam Darnold passes against the California Golden Bears during the first quarter at California Memorial Stadium on Sept. 23, 2017 in Berkeley, California. Getty Images

It seems almost inevitable that a few of the best teams in college football are going to suffer upsets in Week 6 of the 2017 season. Eleven of the teams ranked in the AP Top 25 Poll are on the road Saturday, according to the latest betting odds.

Playing on the road against conference rivals, No.13 Miami and No.11 Washington State are favored by just a field goal, despite being undefeated. The betting line between No.19 San Diego State and unranked UNLV is in single digits, as well.

No.1 Alabama is the biggest road favorite, giving nearly four touchdowns to Texas A&M. The Crimson Tide have been unbelievably dominant, winning their first two SEC games by a combined 122 points.

Two ranked teams are underdogs Saturday. No.23 West Virginia is getting 13 points in their visit to No.8 TCU. No. 20 Utah is an underdog, even though they are at home and facing an opponent that isn’t in the AP Top 25 Poll. Stanford has two losses on the year, though both defeats came to teams that are currently in the top 20.

No.14 USC is the biggest overall favorite on the schedule. The Trojans, Ohio State and Oklahoma are all favored by at least 30 points.

No.7 Michigan is a 10-point home favorite against Michigan State in the biggest rivalry game of the weekend. The point spread has dropped from 13 points earlier in the week.

No.21 Florida is just a 2.5-point favorite at home against LSU. The Tigers fell out of the Top 25 after an embarrassing loss to Troy.

The only game on the Thursday night schedule featured two ranked teams. No.24 NC State won at home against No.17 Louisville.

Below are the complete betting lines for all the Week 6 college football games with top-25 teams, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas and online, via OddsShark.

Wake Forest (+21.5) at No.2 Clemson, 47.5

Iowa State (+30) at No.3 Oklahoma, 63

No.4 Penn State (-13) at Northwestern, 51

No.5 Georgia (-16.5) at Vanderbilt, 40.5

Ole Miss (+22.5) at No.12 Auburn, 56

No.23 West Virginia (+13) at No.8 TCU, 66

No.13 Miami (-3) at Florida State, 45

No.21 Notre Dame (-14.5) at North Carolina, 63

LSU (+2.5) at No.21 Florida, 45

Maryland (+31.5) at No.10 Ohio State, 61

Oregon State (+34) at No.14 USC, 58.5

No.1 Alabama (-26.5) at Texas A&M, 54.5