The third-largest chemical maker in the United States said net income rose to $1.17 billion, or $1.26 per share, from $417 million, or 41 cents per share, a year earlier.
Excluding one-time items, the company posted a profit of $1.17 per share.
Analysts expected earnings of 93 cents per share, according to Thomson Reuters I/B/E/S. If was not immediately clear if the numbers were comparable.
Revenue rose 25.6 percent to $8.62 billion. Analysts expected $8.27 billion.
DuPont raised its 2010 earnings forecast to a range of $2.90 to $3.05 per share, excluding one-time items. It had previously forecast $2.50 to $2.70.
Analysts expect 2010 earnings of $2.64 per share.
The Wilmington, Delaware-based company, also known as E.I. du Pont de Nemours & Co, is a component of the Dow Jones industrial average <.DJI> and is considered a key gauge of economic health.
DuPont makes a wide range of products beyond basic chemicals, including Kevlar, used in bulletproof vests; Tyvek, a popular home insulation wrap; and Teflon, used in nonstick cookware.
Shares of DuPont rose 2.1 percent to $39.80 in premarket trading.
(Reporting by Ernest Scheyder; Editing by Lisa Von Ahn)