When and where: The international friendly kicks-off from the Wankdorf Stadium in Berne, Switzerland, at 3 p.m. ET. Coverage in the U.S. will be provided by RAI International. The match can also be seen in delayed form from 4 p.m. on Gol Tv. Viewers in the U.K. can watch the match on ITV1, with a live stream available at ITV.com.
Preview: It's less than two months since Italy ousted England on penalties to reach the semifinals of Euro 2012. Yet the two European powers meet once more in Switzerland on Wednesday, though there will be few players featuring who were on the pitch in Kiev.
While the match supposedly acts as preparation for the start of World Cup qualification campaigns next month, both sides will field experimental lineups.
England coach Roy Hodgson has decided to leave out the experienced quartet of Wayne Rooney, Steven Gerrard, John Terry and Ashley Cole. In addition, Joe Hart, Theo Walcott, Alex Oxlade-Chamberlain and Daniel Sturridge have all withdrawn through injury.
Despite being 34 and having missed the European Championships through injury, Frank Lampard is included, though, and will captain the side. Alongside Lampard in the midfield could well be Michael Carrick. The Manchester United man is a surprise inclusion in the squad having reportedly asked not to be considered for selection this summer.
"Luckily he has reconsidered his decision and he's keen to play for us, so I've got another quality player coming back that I didn't have during Euro 2012," Hodgson said, according to Fifa.com.
Italy coach Cesare Prandelli's squad has also been hit with absentees, with his large contingent of Juventus as well as Napoli players unavailable after featuring in Sunday's Supercoppa Italiana. There is also disappointment in the absence of the always engrossing Mario Balotelli with an eye infection.
As a result, a number of young players are set to be given a chance to impress. New Paris Saint-Germain midfielder Marco Verratti is expected to start, while Stephan El Shaarawy and Mattia Destro are likely to lead the line.
To Prandelli, the experimental side represents an important beginning to preparations for the 2014 World Cup.
"The plan is to prepare for the next two years, starting from now, by working out which young players are ready to make the grade," he said, according to Fifa.com. "That is the challenge against England on Wednesday night and it is an important one. I can see the desire to get off to a good start in many of my players' eyes."
D: Walker, Cahill, Jagielka, Baines
M: Lampard, Carrick
Milner, Cleverley, Young
D: Abate, Astori, Ogbonna, Balzaretti
M: Verratti, De Rossi, Nocerino
F: Destro, El Shaarawy
Prediction: With such an unusual look to both sides, it is difficult to forecast how the match will pan out, while it would be erroneous to read too much into the result. After Italy dominated England for 120 minutes of their quarterfinal at Euro 2012, there will be interest in whether Roy Hodgson will attempt to make his side more proactive.
With little on the line, both sides will be fairly happy to settle for a draw.
England 1-1 Italy