The new European Columbus science module was removed from the Atlantis space shuttle and attached to the International Space Station.
Leland Melvin and Dan Tani used a robot arm to remove the Columbus from Atlantis' cargo.
Columbus has started its trip to the New World, said flight engineer Daniel M. Tani, as the laboratory rose from the cargo bay.
The $2 billion Columbus will add 2,600 cubic feet of volume to the space station as well as doubling the research capability.
The work of moving and installing Columbus was initially started by Hans Schlegel, an ESA astronaut from Germany and was to perform the spacewalk although he couldn't due to the illness he contracted as the Atlantis docked with the station, forcing a one day delay in the space walk and Mr. Love was brought in as a substitute for the task.