The deal is due to close on Monday and will then be announced to the public, TheMarker said on Sunday.
Guardium started as an Israeli firm in 2002 but moved to Boston in 2003. It has about 60 employees and all will profit from the sale, TheMarker cited a source close to the company as saying.
The company had raised $21 million from venture capital funds such as Ascent Venture Partners, Israel's StageOne Ventures and Veritas, and Cisco Systems
Guardium is a subsidiary of Israel's Log-On Software. Officials at Log-On declined to comment on the report.
Guardium's product enables companies to extend the use of corporate applications to customers, partners and providers while ensuring that the databases used by those applications are shielded.
(Reporting by Tova Cohen; Editing by Clarence Fernandez)