JetBlue Airways CFO Ed Barnes resigned, the company announced late Tuesday.
Mark Powers, JetBlue's treasurer, will serve as interim CFO as the company seeks a replacement.
Barnes joined the New York-based low-cost airline in 2006 as vice president of cost management and financial analysis before his CFO appointment in 2008.
No reason was stated for his departure, but New York-based JetBlue's president and CEO Dave Barger said in the statement that the company had benefited from a stronger financial discipline under Barnes' leadership.
A JetBlue spokesperson said Barnes was leaving on good terms to pursue other interests, and the decision didn't come as a surprise to the CEO, according to an Associated Press report.
JetBlue shares fell 2 percent in early trading to $4.53. They have lost 31 percent in 2011.