The lives of Kennedy family members, noted for their extraordinary accomplishments, have also been marked by tragedy, including the assassinations of President John Kennedy and of Senator Robert Kennedy.
Following is a chronology of some of the tragedies that befell the storied U.S. political dynasty:
1941: Rosemary Kennedy, the oldest daughter of Joseph and Rose Kennedy, who was mentally disabled, was institutionalized for the rest of her life after a lobotomy reduced her abilities. She died in 2005.
1944: Joseph Kennedy Jr., the oldest of the nine Kennedy children, died at age 29 in a plane crash over the English Channel during World War Two while flying a mission.
1948: Kathleen Kennedy Cavendish, the fourth of the Kennedy children, was killed in a plane crash in France at age 28.
1963: President John Kennedy was assassinated on November 22 while riding in a presidential motorcade with his wife in Dallas, Texas, at age 46.
1964: Senator Edward Kennedy, the youngest in the family, narrowly escaped death in a plane crash that killed an aide.
1968: Senator Robert Kennedy was assassinated on June 5 in Los Angeles at age 42, just after he won California's Democratic presidential primary election.
1969: Edward Kennedy drove off a bridge on his way home from a party on Chappaquiddick Island in Massachusetts. An aide in the car with him, Mary Jo Kopechne, died in the accident.
1984: David Kennedy, a son of Robert, died of a drug overdose at age 28.
1997: Another of Robert Kennedy's sons, Michael, died in a skiing accident in Aspen, Colorado, at age 39.
1999: John Kennedy Jr. along with his wife and sister-in-law were killed when the plane he was flying crashed in the waters off Martha's Vineyard in Massachusetts.
(Compiled from Web sites by the World Desk Americas)