The maker of Kleenex tissues and Huggies diapers earned $492 million, or $1.17 per share, up from $419 million, or $1.01 per share, a year earlier.
Sales rose 8.4 percent to $4.98 billion, while the volume of goods sold rose about 2 percent. The acquisitions of I-Flow Corp and Jackson Safety added a point of sales growth.
Sales of healthcare products such as gloves and face masks jumped 22.1 percent, spurred by demand following the H1N1 flu pandemic.
Analysts, on average, expected Kimberly-Clark to earn $1.25 per share on sales of $4.92 billion, according to Thomson Reuters I/B/E/S.
The company forecast 2010 earnings of $4.80 to $5 per share, with sales up 5 percent to 6 percent and volume up 2 percent to 3 percent. Analysts had been anticipating a 2010 profit of $5.14 per share.
(Reporting by Jessica Wohl; editing by John Wallace)