When and Where: The Premier League encounter from the Etihad kicks-off at 3.45 p.m on Wednesday. ET. A live stream of the match is available on ESPN3. The game will also be on ESPN2.
Preview: Both Manchester City and Chelsea have a huge incentive to get a result in Wednesday's Premier League encounter at the Etihad.
After topping the standings for much of the season, City now find themselves four points behind Manchester United and need to win this game-in-hand to keep the pressure on their local rivals.
City's problems of late have come away from home where they have lost four games this campaign, the most recent being their last league game against Swansea.
At the Etihad it has been a very different story, though. Indeed, Roberto Mancini's men have won all 14 of their league games at home this season.
Chelsea need the points themselves to close the gap on Arsenal in the race for fourth place and a Champions League berth for next season.
The West Londoners should be on a high after a dramatic Champions League comeback against Napoli last week and an impressive 5-2 result over Leicester in the FA Cup at the weekend.
Team News: Manchester City manager Roberto Mancini has hinted that Carlos Tevez will be back on the Manchester City bench on Wednesday. If that happens then expect the camera to spend almost as much time focused on the dugout as it does on the pitch.
City's main injury worries are in the center of their defense. Manicni confirmed at Tuesday's press conference that Joleon Lescott will miss the match with a hip injury.
Meanwhile, Lescott's regular defensive partner and City captain Vincent Kompany is doubtful for the game as he recovers from a calf injury sustained in the first-leg of the Europa League tie with Sporting Lisbon.
City will, though, welcome back Pablo Zabaleta and Gareth Barry from injury.
Chelsea have defensive concerns of their own with skipper John Terry ruled out after playing two-games in quick succession following his speedy return from a knee injury.
Fernando Torres may get a start after breaking his drought by scoring twice at the weekend against Leicester. Although it could be that interim boss Roberto Di Matteo sees the combative Didier Drogba as more suitable to the lone striking role in a tough away fixture.
Prediction: Manchester City have been imperious at home this season and have had the chance to refresh after almost a week since their last outing.
Chelsea, on the other hand, will be playing their third game in the space of a week and the effects could be evident against City, given their aging squad.
City should get the win, but their defensive problems mean that Chelsea will make it close.
Manchester City 2-1 Chelsea