Stocks held their losses on Friday after the Institute for Supply Management-Chicago said its index of Midwest business activity fell in May.

The Dow Jones industrial average <.DJI> was down 57.21 points, or 0.56 percent, at 10,201.78. The Standard & Poor's 500 Index <.SPX> was down 6.07 points, or 0.55 percent, at 1,096.99. The Nasdaq Composite Index <.IXIC> was down 14.59 points, or 0.64 percent, at 2,263.09.

(Reporting by Ryan Vlastelica; editing by Jeffrey Benkoe)