Most of the games on the Week 10 schedule are expected to be close, though a few stand out as potential blowouts. Two teams are favored by double-digits, and one game features nearly the biggest betting line of the entire 2016 NFL season.

For the second time this year, the San Francisco 49ers are underdogs of at least 13 points. They were 14-point underdogs against the Carolina Panthers in Week 2 in a game they ultimately lost by 19 points. The Arizona Cardinals have already defeated the 49ers by double-digits earlier this year, and San Francisco hasn’t been victorious since the season opener.

The one-win 49ers are bigger underdogs than the winless Cleveland Browns, who are getting 10 points against the Baltimore Ravens on Thursday night. Cleveland nearly defeated Baltimore in Week 2, but the team hasn’t won a game since they beat San Francisco on Dec. 13, 2015.

Eight of the 14 Week 10 games feature a point spread of less than a field goal. The contest between the Atlanta Falcons and Philadelphia Eagles is a pick’em, and it also has the week’s highest over/under.

The Dallas Cowboys are tied for the NFL’s best record with the New England Patriots, but the NFC East leaders are underdogs in their trip to Pittsburgh. New England is more than a touchdown favorite over the visiting Seattle Seahawks on Sunday night.

The Buffalo Bills, Detroit Lions, Indianapolis Colts and Oakland Raiders all have byes in Week 10. Oakland has sole possession of first place in the AFC West just ahead of the Kansas City Chiefs and Denver Broncos, both of whom are underdogs in their upcoming contests.

Below are the complete betting lines for all the Week 10 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas and online, via OddsShark.

Cleveland Browns (+10) at Baltimore Ravens, 45

Houston Texans (-1.5) at Jacksonville Jaguars, 42.5

Kansas City Chiefs (+3) at Carolina Panthers, 44

Denver Broncos (+1.5) at New Orleans Saints, 49

Los Angeles Rams (+2) at New York Jets, 39.5

Atlanta Falcons (PK) at Philadelphia Eagles, 50.5

Minnesota Vikings (+3) at Washington Redskins, 42

Green Bay Packers (-2.5) at Tennessee Titans, 49.5

Chicago Bears (+1.5) at Tampa Bay Buccaneers, 45

Miami Dolphins (+3.5) at San Diego Chargers, 49

San Francisco 49ers (+13.5) at Arizona Cardinals, 48.5

Dallas Cowboys (+2.5) at Pittsburgh Steelers, 50

Seattle Seahawks (+7.5) at New England Patriots, 48.5

Cincinnati Bengals (+2.5) at New York Giants, 47