The Cardinals are expected to have a close game on the road against the Rams. The two teams kick off Week 5 on Thursday Night Football.
Both the Browns and Saints have yet to win a game this year. Cleveland is the only double-digit underdog in Week 5. The Giants are 10-point favorites against the Browns.
New Orleans is favored at home, despite starting the season at 0-4. The Chargers are 3-1, but San Diego is still a 3.5-point underdog against the Saints.
Peyton Manning and Tom Brady are ready to square off in their annual matchup. The Broncos visit the Patriots. Denver is a 7-point underdog heading into New England.
The Texans and Jets will close out the week on Monday Night Football. Houston is a 7.5-point favorite heading into New York. Mark Sanchez is expected to start over Tim Tebow, despite his struggles this season.
Four teams have the week off. The Cowboys, Lions, Raiders and Buccaneers won’t play in Week 5.
Below are the complete betting lines for all the Week 5 games, including the point spreads and totals. These are the consensus odds from multiple sportsbooks in Las Vegas.
Arizona (-1.5) at St. Louis, 38.5
Atlanta (-3) at Washington, 50
Philadelphia (+3.5) at Pittsburgh
Green Bay (-7) at Indianapolis, 48.5
Cleveland (+10) at New York Giants, 44
Tennessee (+5.5) at Minnesota, 43.5
Miami (+4.5) at Cincinnati, 45
Baltimore (-4.5) at Kansas City, 46
Seattle (+3) at Carolina, 44
Chicago (-4) at Jacksonville, 39.5
Denver (+7) at New England, 51.5
Buffalo (+9.5) at San Francisco, 44.5
San Diego (+3.5) at New Orleans, 54
Houston (+7.5) at New York Jets, 40.5
Dallas, Detroit, Oakland, Tampa Bay