The top after-market NASDAQ losers Wednesday were: Sigma Designs, Semtech Corp, Amylin Pharmaceuticals, Alkermes plc, Daktronics, Jamba, American Capital Agency, VOXX International, Star Scientific and Amyris.

Sigma Designs, Inc. (SIGM) stock plunged 5.85 percent to $5.15 in aftermarket trading session. The company swung to fourth quarter net loss of $0.58 per share compared to net income of $0.08 per share in the same period a year-ago.

Semtech Corp. (SMTC) stock plunged 5.69 percent to $26.54 in aftermarket trading session. Its fourth quarter net profit declined to $12.4 million or $0.19 per share from $26.0 million or $0.39 per share in the same period a year-ago.

Amylin Pharmaceuticals, Inc. (AMLN) stock plunged 4.7 percent to $15.41 in aftermarket trading session. The company announced that it is offering to sell shares of its common stock in an underwritten public offering.

Alkermes plc. (ALKS) stock declined 3.93 percent to $16.62 in aftermarket trading session. The company announced that it has commenced an underwritten public offering, subject to market and other conditions, of 13,900,000 ordinary shares held by a subsidiary of Elan Corporation, plc, pursuant to an effective shelf registration statement.

Daktronics, Inc. (DAKT) stock declined 3.19 percent to $8.20 in aftermarket trading session.

Jamba, Inc. (JMBA) stock declined 2.84 percent to $2.05 in aftermarket trading session. The company reported fourth quarter net loss of $10.3 million or $0.15 per share compared to loss of $13.2 million or $0.21 per share in the same period a year-ago.

American Capital Agency Corp. (AGNC) stock fell 2.41 percent to $29.54 in aftermarket trading session. The company announced Wednesday that it priced a public offering of 62,000,000 shares of common stock for total estimated gross proceeds of approximately $1.8 billion.

VOXX International Corp. (VOXX) stock declined 2.38 percent to $12.26 in post market trading session.

Star Scientific, Inc. (CIGX) stock fell 2.03 percent to $3.86 in post market trading session. The company stock surged nearly 7 percent in regular session.

Amyris, Inc. (AMRS) stock declined 1.92 percent to $4.60 in post market trading session.