Array Biopharma Inc, CombiMatrix Corporation, Himax Technologies Inc, Rio Tinto plc, Orange SA, ArcelorMittal, Netflix Inc, STMicroelectronics, ISIS Pharmaceuticals and Frontline Ltd are among the companies whose shares are moving in pre-market trading on Tuesday.

Gainers

Array Biopharma Inc (NASDAQ:ARRY) stock surged 12.95 percent to $6.28 in pre-market trading. The company’s shares rose following the announcement of positive results from a placebo-controlled, randomized, double-blind Phase 2 trial involving people with mild-to-moderate persistent allergic asthma for ARRY-502, an oral CRTh2 antagonist.

CombiMatrix Corporation (NASDAQ:CBMX) shares rallied 9.77 percent to $3.37 in pre-market trading after the molecular diagnostics company announced that it has entered into a contractual agreement with the health insurer, Blue Shield of California (BSCA), for coverage of its diagnostic laboratory services.

Himax Technologies Inc (NASDAQ:HIMX) shares rose 2.67 percent to $6.92 in pre-market trading. The company's stocks continued a rally for the second straight day on Tuesday, after it was announced on Monday that Google Inc. (NASDAQ:GOOG) has agreed to invest in the company's subsidiary, Himax Display Inc., to fund production upgrades, expand capacity and further enhance production capabilities at HDI's facilities, which produce liquid crystal on silicon chips and modules used in Google Glass, head-up display (HUD) and pico-projector products. 

Orange SA (NYSE:ORAN) stock advanced 2.33 percent to $10.10 in pre-market trading. The company's stock has a 52-week low of $9.10, a 52-week high of $14.28 and $25.93 billion in market capitalization.

ArcelorMittal (NYSE:MT) stock climbed 2.20 percent to $13.00 in pre-market trading. The stock has a 52-week low of $10.83, a 52-week high of $17.99 and $19.70 billion in market capitalization.

Rio Tinto plc (NYSE:RIO) stock rose 2.48 percent to $45.80 in pre-market trading.  The company's stock has a 52-week low of $39.14, a 52-week high of $60.45 and $82.59 billion in market capitalization.

Losers

Netflix Inc (NASDAQ:NFLX) stock fell 5.71 percent to $247.00 in pre-market trading. Netflix’s shares slumped despite the company posting strong earnings for the second quarter, as its re-launched comedy series "Arrested Development" failed to bring in the expected number of subscribers.   

STMicroelectronics N.V. (NYSE:STM) declined 5.52 percent to $9.25 in pre-market trading. The company's shares have a 52-week low of $4.51, a 52-week high of $10.05 and a market capitalization of $8.69 billion.

ISIS Pharmaceuticals Inc (NASDAQ:ISIS) stock declined 2.59 percent to $30.12 in pre-market trading. The company announced data from a Phase 2 study of ISIS-APOCIIIRx in patients with high-to-severely high triglycerides on stable doses of fibrates, which found ISIS-APOCIIIRx to be generally safe and well-tolerated with the most common adverse event being injection-site reactions.

Frontline Ltd. (NYSE:FRO) stock fell 2.49 percent to $2.35 in pre-market trading. The company's shares rose more than 6 percent on Monday in regular trading after it was upgraded by analysts at Global Hunter Securities from a “reduce” rating to a “neutral” rating in a research report issued to clients and investors on Friday.