The top pre-market NASDAQ Stock Market gainers are: Wet Seal, Adolor, Limelight Networks, Cree, and Central European Media Enterprises. The top pre-market NASDAQ Stock Market losers are: Motricity, Amtech Systems, Partner Communications Company, Finisar, and ASML Holding.

Gainers

Wet Seal Inc. (WTSLA) stock jumped 12.55 percent to $5.20 in the pre-market trading.

Adolor Corp. (ADLR) stock soared 12.22 percent to $2.48 in the pre-market trading. The company announced positive, statistically significant top line results from its two Phase 2 studies of ADL5945 in chronic non-cancer pain patients with opioid-induced constipation (OIC). ADL5945, a peripherally-acting mu opioid receptor antagonist, is an investigational drug being evaluated for the treatment of OIC as well as other associated gastrointestinal (GI) complications. Both randomized, double-blind, placebo-controlled studies were identical in design; Study 242 evaluated 0.25 mg and 0.10 mg of ADL5945 administered twice daily (BID) and Study 243 evaluated 0.25 mg of ADL5945 administered once daily (QD).

Limelight Networks, Inc. (LLNW) stock advanced 11.06 percent to $2.31 in the pre-market trading. The company said Limelight Dynamic Site Platform is offering several new features in its latest series of updates. An upgrade of prior technology, acquired by the purchase of Clickability in May 2011, these updates include extensive Web Content Management capabilities for enterprise marketers and online publishers. The latest Dynamic Site Platform updates allow enterprise marketers and online publishers to more easily manage their web content with enhanced work-flow, better leverage personalization and targeting tools for more engaging web experiences, and seamlessly create compelling mobile experiences.

Cree Inc. (CREE) stock climbed 10.92 percent to $32.71 in the pre-market trading. Profit for the fourth quarter was $19.8 million or $0.18 per share, down from $52.8 million or $0.48 per share last year. Adjusted earnings were $30.6 million or $0.28 per share, lower than last year's $60.1 million or $0.55 per share. Revenue declined to $243 million from $264.6 million. Analysts had expected profit of $0.27 per share on revenue of $233.82 million. For the first quarter, the company expects profit of $0.14 to $0.17 per share, adjusted earnings of $0.25 to $0.28 per share and revenue of $245 million to $255 million, while Street predicts profit of $0.31 per share on revenue of $253.40 million.

Central European Media Enterprises Ltd. (CETV) stock increased 4.02 percent to $13.20 in the pre-market trading.

Losers

Motricity, Inc. (MOTR) stock plunged 46.81 percent to $2.42 in the pre-market trading. Adjusted earnings for the second quarter were $2.0 million or $0.04 per share, down from $3.7 million or $0.09 per share last year. Revenue grew 14 percent to $34.6 million. Analysts had expected a profit of $0.09 per share on revenue of $37.08 million. Looking ahead into the third quarter, the company expects to report approximately break-even results on adjusted EBITDA and adjusted loss of about $4 million. The company anticipates third quarter revenue of $31.5 million to $32.5 million, while Street predicts $45.48 million.

Amtech Systems Inc. (ASYS) stock plummeted 16.06 percent to $13.90 in the pre-market trading. The company expects fourth quarter revenue of $53 million to $56 million, while Street predicts $61.10 million. For the fiscal 2011, the company reiterated its revenue outlook of $240 million to $243 million, while Street predicts $245.06 million. The company expects operating margins in the fourth quarter to be negatively impacted by: lower shipment volumes, expected higher material costs, and substantially higher research and development costs resulting from its solar development programs, including its solar ion implant project. The company also said operating results could also be impacted by the timing of system shipments, the net impact of revenue deferral on those shipments, and recognition of revenue based on customer acceptances, all of which can have a significant effect on operating results.

Amtech reported its third quarter earnings of $7.30 million or $0.74 per share, higher than last year's $3.88 million or $0.42 per share. Revenue grew to $71.87 million from $43.07 million, on higher system shipments to customers in the solar industry, partially offset by an increase in the amount of revenue deferred. Analysts had expected profit of $0.70 per share on revenue of $70.21 million.

Partner Communications Company Ltd. (PTNR) stock fell 7.80 percent to $11 in the pre-market trading. Profit for the second quarter declined 30 percent to 205 million Israeli shekel or $60 million. Earnings per share fell to 1.31 Israeli shekel from 1.88 Israeli shekel. Revenue rose to 1.89 billion Israeli shekel or $553 million from 1.68 billion Israeli shekel. The company said its board resolved to adopt a buy-back plan, according to which it may, from time to time, repurchase its Series A Notes, which are traded on the Tel Aviv Stock Exchange or TASE. Under the Plan, the company is authorized to repurchase the Series A Notes up to a total amount of NIS 200 million or about $59 million in transactions on the TASE or outside TASE, until March 31, 2012.

Finisar Corp. (FNSR) stock declined 2.24 percent to $13.54 in the pre-market trading.

ASML Holding NV (ASML) stock decreased 1.73 percent to $32.97 in the pre-market trading.