A portion of the 405 Freeway from the Hollywood Hills to the 10 Santa Monica Freeway will close for the weekend starting Friday, July 15.

Caltran workers will work on demolishing a bridge during that time, and the freeway portion is expected to reopen on Monday, July 18.

The San Diego I-405 Freeway is the most clogged freeway system in the city. and drivers are expected to prepare for the closure and limit travel, if at all.

The closure is expected to affect north-south running streets as well as east-west roads throughout Los Angeles.

In an effort to alert commuters about the upcoming closer, officials have even turned to celebrities with large Twitter followings to get the message out to fans to avoid the area.

Los Angeles International Airport is also urging travelers to prepare for a tough drive to the airport, and warning them that re-booking tickets may be a problem due to peak travel season should they miss their flight.

The 405 is a major transportation conduit to the LAX, which estimates some 170,000 passengers coming and going to the airport each day.

Los Angeles World Airports spokesperson Nancy Castles advised Ride the rails to Union Station and catch our FlyAway [shuttle] to LAX, or ride the Green Line directly into LAX, or, if they really must drive, to really plan for several hours in advance of that.

Prime Time Shuttle is offering special Carmageddon deals' for people, as their drivers are familiar with alternate routes around the 405 closure.

L.A. County Metro is also offering free rides on 26 of its buses and certain rail lines on Carmageddon weekend.