The story takes place 10 years after the original game, which was released for the PlayStation in 1996. Players will be able to play through two storylines--one with Leon and one with Chris. Leon's story takes place in Tall Oaks, which is an English-speaking area that is probably somewhere in the United States according to the Resident Evil Wikia. The story following Chris takes place in China.
An image of the Resident Evil 6 logo was first leaked at Comic-Con in San Diego on July 22nd 2011. The leaked logo included a date, September 15, 2011, which was the date of the Tokyo Game Show. Capcom did not unveil more information about the game at TGS, though a fake video did make its way to the web. Multiple sources denied that the video was an official Resident Evil 6 trailer (known as Biohazard in Japan) according to 1UP.
In the first Resident Evil, the fictitious, remote Midwestern city, Raccoon City was destroyed during an outbreak of the Tyrant virus, more commonly referred to as the T-virus. The T-virus was originally created by the Umbrella Corporation, which had several plants just outside of Raccoon City, as a form of biological warfare. The virus that was being developed turned humans into zombie-like mutants that mauled the uninfected. The first game is built on the premises of surving the desolate Raccoon City and eventually escaping via a helicopter.
Resident Evil 6 starts with the President of the United States revealing the truth behind what happened in Raccoon City. Leon Kennedy is scheduled to make the official announcement with the President, who's his personal friend, but there's a bioterrorist attack just before the speech is given. At the same time, Chris Redfield arrives in China, which is also facing several bioterrorist attacks. The entire world is united against the threat of bioterrorist attacks.
Judging by the trailer, it appears that the game will be played from the third-person point-of-view, with the camera hanging just over the protagonists' shoulder. According to Resident Evil 6 posters that have appeared at Gamestop, the game will be available on both the PS3 and Xbox 360.