Exactech Inc., which makes bone and joint restorations products, said Friday it will sell 877,391 shares at $23 each. The company expects to raise $20.2 million from the sale, or $18.8 million after expenses and placement agency fees.

Alphatec Holdings Inc., which makes products to treat scoliosis and degenerating spinal discs, said Friday Steven Yasbek will resign as chief financial officer and treasurer May 12 to pursue other interests.

Shares of American International Group fell sharply in premarket trading Friday after it posted a $7.8 billion first-quarter loss and said it plans to raise $12.5 billion in new capital.

Adolor Corp. said Friday that the Food and Drug Administration won't be making a decision on approval of the company's Entereg drug for post-surgery bowel blockage by Saturday, the scheduled action date.

Shares of drug developer Durect Corp. surged Thursday, after the company reported a smaller first-quarter loss on lower costs and greater research and development partnership revenue.

Stryker Corp. said today it will invest $50 million in 2008 to improve its quality systems and compliance at the time it deals with three warni

Mylan Inc. manufacturer of generic pharmaceutical products said on Thursday an extended first quarter loss and a large increase on its revenue triggered by the purchase of Merck KGaA in October.

Bristol-Myers Squibb Co. and Japanese partner Otsuka Pharmaceutical Co. said Thursday federal regulators expanded approval for Abilify to aid with the treatment of bipolar disorder.

Generic drug maker Mylan Inc. Thursday said its first-quarter loss widened due to a $385 million noncash goodwill impairment charge related to its specialty business, though adjusted results beat analyst expectations.

Medical device maker Boston Scientific Corp. said Thursday a Canadian court dismissed a patent infringement lawsuit filed against the company by rival Johnson & Johnson.

Some of the nation's largest pharmaceutical companies defended their TV advertisements Thursday from Democrats pushing for tougher marketing restrictions.

U.S.-traded shares of Mindray Medical International Ltd. rose sharply on Thursday after the China-based medical device maker said its first-quarter profit climbed 62 percent on growth in both domestic and international markets.

Medicis Pharmaceutical Corp. raised its full-year profit guidance Thursday after its first-quarter results topped expectations. The company expects 2008 profit between $1.49 and $1.58 per share on revenue between $529 million and $538 million. In February, the company set full-year profit guidance b...

Shares of large pharmaceutical companies closed mostly higher Thursday with the broader market, despite the appearance before Congress of executives from several major companies aiming to defend their advertising practices.

Health care equipment and supply stocks ended higher Thursday, in line with the broader market, as investors reacted favorably to retreating oil prices and better-than-expected retail sales reports.

Health care stocks mostly finished higher Thursday, with pharmacy benefits manager Express Scripts Inc. making the biggest gains. Here are the day's results for a few key health care providers and service stocks:

Among the earnings projection stories for Thursday, May 8, from AP Financial News: SUMMIT, N.J. (AP) _ Biotechnology company Celgene Corp. on Thursday raised its full-year sales estimate to $2.1 billion, a nearly 60 percent increase over 2007 revenue.

Shares of hospice care provider Odyssey Healthcare Inc. soared Thursday after posting adjusted first-quarter profit that beat Wall Street predictions.

Shares of Barr Pharmaceuticals Inc. plunged Thursday after the drug developer reported first-quarter profit below Wall Street expectations and slashed its 2008 forecast, leading at least one analyst to downgrade the stock.