Tank fire killed at least three civilians and wounded dozens in the besieged Syrian city of Homs on Saturday, activists and residents said, casting doubt on whether an Arab League plan can end months of bloodshed triggered by a popular uprising.

The deaths, on the eve of the main Muslim feast of Eid al-Adha, brought to 80 the number of civilians reported killed in Homs since Tuesday by troops trying to crush protests against President Bashar al-Assad and an emerging armed uprising.

Whole buildings have been gutted by tank fire. Bread has run out and people who get hit in the streets are dying from their wounds on the spot because no one can reach them, said Samer, a local activist.

The authorities say security forces are fighting militant armed gangs who have been killing civilians and prominent figures in Homs, a city of 1 million, 140 km (85 miles) north of Damascus. State media said this week that several terrorists had been killed and arsenals seized, including rocket-propelled grenade launchers, petrol bombs and explosives.

The government says Islamist militants and foreign-backed armed gangs have killed 1,100 members of the security forces since the uprising against 41 years of Assad family rule began in March. The United Nations says more than 3,000 people have been killed in the crackdown.

AMNESTY OFFER

On Friday state television announced an amnesty to anyone with weapons if they reported to police within a week, as long as they did not commit any crimes of killing.

The same day, security forces killed at least 19 people and wounded dozens across Syria, activists said.

The amnesty did not appear to be part of the Arab League plan, accepted by Syria on Wednesday, under which the army would leave turbulent cities, political prisoners would walk free and a dialogue with the opposition would begin within two weeks.

The opposition has so far rejected talks with Assad as long as violence continues and has said the only way to restore peace is for the president to step down immediately.

U.S. State Department spokeswoman Victoria Nuland reacted dismissively when asked if she thought Syrians should participate in the amnesty, saying: I wouldn't advise anybody to turn themselves in to regime authorities at the moment.

She also accused the Syrian government of failing to carry through on the Arab League plan and said the United States had no confidence that it would. We have a long, deep history of broken promises by the Assad regime, she told reporters.

The Syrian government condemned irresponsible statements ... that aim to ignite sectarian strife and support the killings and terrorism being practised by the armed groups against Syria's citizens.

In Homs, the bombardment was concentrated on Bab Amro, a poor residential district several kilometres from the centre, where insurgents and an increasing number of army defectors had taken refuge, residents said.

The humanitarian situation in Bab Amro has become horrific. Inhabitants are reporting a total siege and dwindling food and medicine supplies, exiled dissident Rami Abdelrahman told Reuters by phone from Britain on Saturday.

SECTARIAN TENSION

Tensions have also grown in Homs between members of its Sunni majority and Assad's minority Alawite sect, after reported tit-for-tat sectarian killings this week.

Restrictions on foreign and local media make it hard to verify accounts of events in Syria.

State television denied that there had been any killings of protesters on Friday. It aired footage that it said was from areas where protests had been reported, showing crowds calmly leaving mosques after prayers. It said four police had been injured by gunfire from armed terrorist groups in Kanaker, south of Damascus.

But YouTube footage, purportedly from many towns and cities, showed thousands of people waving flags, with some shouting: Mother do not cry, Bashar's days are numbered!

One clip, from the town of Taybet al-Imam, near Hama, showed crowds marching along a main street where huge Syrian flags from the pre-Baathist era were draped over buildings, along with the Libyan flag adopted by the rebels who overthrew Muammar Gaddafi.

The people want the execution of Assad! protesters shouted at a rally in the town of Deir Baalba near Homs.

(Editing by Kevin Liffey)