The top after-market Nasdaq gainers Tuesday were InterMune Inc, Aruba Networks Inc, Transcept Pharmaceuticals Inc, Resources Connection Inc and Education Management.

The top after-market Nasdaq losers were Xyratex Ltd, Synaptics Inc, Rigel Pharmaceuticals Inc, Sarepta Therapeutics Inc and Acme Packet Inc.

Gainers

InterMune Inc (ITMN) shares climbed 10.17 percent to $9.75 in after-hours trading Tuesday.  The company's shares surged after it announced that Health Canada has approved Esbriet® (pirfenidone) for the treatment of mild to moderate idiopathic pulmonary fibrosis (IPF) in adult patients.  

Shares of Aruba Networks Inc (ARUN) rose 9.73 percent in the post-market session to close at $22.38.  The shares of the company dropped 6.21 percent in regular trade Tuesday.  

Transcept Pharmaceuticals Inc (TSPT) shares advanced 5 percent to $5.46 in post-market trading. The company shares have a 52-week trading range of $5.09-$12.99 and a market capitalization of $96.53 million.

Resources Connection Inc (RECN) shares gained 4.60 percent and reached $13.86 in after-hours trading. The company stocks gained after the company announced higher financial results for its fiscal first quarter.  The company's net income for the first quarter that ended Aug. 25, 2012, was $4.8 million, or $0.12 per diluted share, in line with analysts’ expectation of $0.12 per share and a higher than the  $2.6 million or $0.06 per diluted share recorded in the previous year for the same quarter. 

Education Management Corporation (EDMC) shares surged 4.29 percent to $3.16 in after-hours trading Tuesday. The shares of the company dropped 4.11 percent in regular trade Tuesday.  

Losers

Xyratex Ltd (XRTX) shares slumped 13.79 percent to $7.50 in the post-market session Tuesday. The UK-based company announced a higher-than-expected decline in the third quarter profit and forecast an unexpected loss for the fourth quarter. Xyratex reported an earnings of 37 cents a share, on revenue of $276 million that missed the analysts’ expectations for 44 cents a share on the sales of $316 million.

Synaptics (SYNA) shares plunged 4.43 percent to $22.87 in the post-market session. The company’s shares had surged 4.63 percent on regular trading Tuesday after it announced that the signature HTC 8X and the HTC 8S Windows Phone 8 smartphones, both featuring high resolution screens in thin and light designs, are driven by Synaptics ClearPad Series 3 solutions. The Synaptics shares were upgraded by investment analysts at Feltl & Co. from a “sell” rating to a “hold” rating in a note issued to investors on Tuesday. 

Rigel Pharmaceuticals Inc (RIGL) shares lost 3.38 percent in after-hours trading to reach $10.00. The company shared declined after it announced that it intends to offer and sell shares of its common stock in an underwritten public offering.

Sarepta Therapeutics Inc (SRPT) shares dropped 3.27 percent to $14.50 in after-hours trading.  The company shares dropped 9.32 percent in regular trade Tuesday.

Acme Packet Inc (APKT) shares declined 3.30 percent to $17.01 in after-hours trading. The company shares gained 9.32 percent in regular trade Tuesday.