The top pre-market NASDAQ stock market losers are: RINO International, Bank of Kentucky Financial, Human Genome Sciences, EDAP TMS, Patterson-UTI Energy, JA Solar Holdings, GT Solar International, Syntel, Acergy, and Sina.

RINO International Corp. (RINO) lost 14.13 percent to $6.14 in the pre-market trading. Law firms Roy Jacobs & Associates, Rosen Law Firm, Glancy Binkow & Goldberg LLP, and Faruqi & Faruqi LLP are investigating possible violations of laws as certain statements regarding the company's business, operations and prospects misrepresented RINO's financial performance.

RINO reported a 48.3 percent fall in third quarter profit that came in below analysts expectations. The company lowered its full year 2010 revenue guidance, lower than analysts forecast, due to weaker than expected third quarter and disruption caused by industry consolidation.

Bank of Kentucky Financial Corp. (BKYF) plunged 7.95 percent to $17.02 in the pre-market session. In a regulatory filing, the company announced the commencement of an underwritten public offering of about $21 million of its common stock.

Human Genome Sciences Inc. (HGSI) plummeted 7.11 percent to $24.04 in the pre-market trading. An advisory panel recommended the FDA to approve the drug Benlsyta or Belimumab for the treatment of autoantibody-positive patients with active systemic lupus erythematosus. The drug is being developed by Human Genome and GlaxoSmithKline (GSK).

EDAP TMS SA (EDAP) fell 5.12 percent to $3.89 in the pre-market trading. The company's third quarter loss narrowed to $2.5 million or 22 cents a share from $8.3 million or 80 cents a share last year. Revenue rose to $7 million from $6.7 million. Analyst expects a loss of 18 cents a share on revenue of $8.41 million.

Patterson-UTI Energy Inc. (PTEN) dropped 3.69 percent to $19.31 in the pre-market session.

JA Solar Holdings Co., Ltd. (JASO) decreased 3.18 percent to $7.60 in the pre-market trading.

GT Solar International, Inc. (SOLR) declined 2.98 percent to $8.14 in the pre-market session.

Syntel, Inc. (SYNT) tumbled 2.89 percent to $47.30 in the pre-market trading. The company said it priced its previously announced secondary public offering of 2.61 million shares of the company's common stock at $47.50 a share. Proceeds to the selling stockholder from the offering are about $45.36 a share.

Acergy SA (ACGY) moved down 1.87 percent to $20.43 in the pre-market session.

Sina Corp. (SINA) fell 1.74 percent to $56 in the pre-market session. The company's third quarter adjusted profit was $31.3 million or 50 cents a share, up from $20.1 million or 34 cents a share last year. Adjusted revenue rose 20 percent to $103.6 million. Analysts expected profit of 43 cents a share on revenue of $103.21 million. Sina expects fourth quarter adjusted revenue of $103 million to $106 million, lower than analysts forecast of $108.65 million.

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