The top pre-market NASDAQ stock market losers are: Subaye, Oncothyreon, American Science & Engineering, ARM Holdings, Tesla Motors, XOMA, CROCS, Micron Technology, ASML Holding, and Sycamore Networks.

Subaye, Inc. (SBAY) lost 12.25 percent to $5.66 in the pre-market session. The company's fiscal 2010 loss from continuing operations was $7.9 million, compared to profit of $8.6 million last year. Revenue rose 46.4 percent to $39.1 million.

Oncothyreon Inc (ONTY) plunged 6.17 percent to $3.65 in the pre-market trading. Merck Serono, a division of Merck KGaA of Darmstadt, Germany, informed Oncothyreon on Dec. 22 that the Independent Data Monitoring Committee (DMC) for the Phase 3 START trial of Stimuvax in non-small cell lung cancer met and the DMC recommendation is to continue the study.

American Science & Engineering Inc. (ASEI) plummeted 5.80 percent to $81.04 in the pre-market session. The company said it received a $3.8 million government order for multiple ZBV Military Trailers or ZBV Mil Trailers.

ARM Holdings plc (ARMH) fell 3.13 percent to $19.79 in the pre-market session.

Tesla Motors, Inc. (TSLA) dropped 2.70 percent to $31.75 in the pre-market trading.

XOMA Ltd. (XOMA) tumbled 2.67 percent to $4.38 in the pre-market session.

CROCS Inc. (CROX) decreased 2.14 percent to $18.29 in the pre-market trading. The company said Russell Hammer resigned as Chief Financial Officer effective December 31, 2010. Hammer resigned to join a Chicago based public company as chief financial officer.

Micron Technology Inc. (MU) slid 1.57 percent to $8.15 in the pre-market session. The company's first quarter profit was $155 million or 15 cents a share, down from $204 million or 23 cents a share last year, due to lower average prices of its DRAM chips. Sales rose 29 percent to $2.25 billion. Analysts had expected profit of 29 cents a share on revenue of $2.38 billion.

ASML Holding NV (ASML) declined 1.41 percent to $37.77 in the pre-market trading.

Sycamore Networks Inc. (SCMR) moved down 1.30 percent to $20.50 in the pre-market session.