The U.S. military mistakenly sent live anthrax bacteria to laboratories in nine U.S. states and a U.S. air base in South Korea, after apparently failing to properly inactivate the bacteria last year, U.S. officials said on Wednesday.
The Pentagon said there was no known suspected infection or risk to the public. But four U.S. civilians have been started on preventive measures called post-exposure prophylaxis, which usually includes the anthrax vaccine, antibiotics or both.
The four face "minimal" risk, said Jason McDonald, a spokesman for the U.S. Centers for Disease Control and Prevention, which has begun an investigation of the incident. The four were "doing procedures that sent the agent into the air," he said.
When anthrax becomes airborne, it can cause a deadly illness called inhalation anthrax. That occurred in 2001, when anthrax sent through the U.S. mail to government and media targets killed five people.
The anthrax, which was initially sent from a Utah military lab, was meant to be shipped in an inactive state as part of efforts to develop a field-based test to identify biological threats, the Pentagon said.
"Out of an abundance of caution, (the Defense Department) has stopped the shipment of this material from its labs pending completion of the investigation," said Pentagon spokesman Colonel Steve Warren.
The CDC said it has launched an investigation of the mishap.
"All samples involved in the investigation will be securely transferred to the CDC "or affiliated labs "for further testing," spokeswoman Kathy Harden said, adding that CDC has sent officials to the labs "to conduct on-site investigations."
The mishap comes 11 months after the CDC, one of the government's top civilian labs, similarly mishandled anthrax.
Scores of CDC employees were potentially exposed to the live anthrax, but none became ill.
That incident and a similar one last spring, in which CDC scientists shipped what they thought was a benign form of bird flu but which was actually a highly virulent strain, led U.S. lawmakers to fault a "dangerous pattern" of safety lapses at government labs.
ANTHRAX SENT TO GOVERNMENT AND PRIVATE FACILITIES
In the latest case, the Army's Dugway Proving Ground in Utah reported in March 2014 that gamma irradiation had inactivated the anthrax stock in question, and along with another Army facility, began shipments that continued through April 2015, a U.S. official said.
The official, who spoke on condition of anonymity, said the suspected live anthrax samples were sent to U.S. federal, private and academic facilities.
The anthrax was sent to laboratories in Maryland, Texas, Wisconsin, Delaware, New Jersey, Tennessee, New York, California and Virginia, officials said.
The four civilians receiving post-exposure prophylaxis are in Delaware, Texas and Wisconsin. "Workers who were not in the same area at the same time are not at risk," the CDC's McDonald said.
On Friday night the Maryland laboratory alerted CDC that it had a live sample; by midday on Saturday, the laboratories were notified, the official said.
Experts in biosafety were astonished by the latest lapse.
"These events shouldn't happen," said Stephen Morse of Columbia University, a former program manager for biodefense at the Pentagon's Defense Advanced Research Projects Agency.
Scientists working with the most dangerous pathogens follow a "two-person rule," never handling samples alone. The second pair of eyes is meant to insure scientists take proper precautions during experiments.
Two people should also vet shipments of supposedly killed anthrax. "We can put greater safeguards in place," Morse said.