A car-ramming targeting Israeli troops in Jerusalem wounded 14 people Thursday while two Palestinians were shot dead in clashes in the occupied West Bank, as violence spiked a week after Washington's controversial Middle East peace plan.

A third person was killed by Israeli officers inside the Old City in east Jerusalem after firing on police, Israeli officials said.

The alleged perpetrator of the car ramming was arrested Thursday evening after a day-long manhunt. The suspect was not immediately identified.

An Israel air strike hits the southern Gaza Strip following new rocket or mortar fire by Palestinian militants
An Israel air strike hits the southern Gaza Strip following new rocket or mortar fire by Palestinian militants AFP / SAID KHATIB

The army said it was deploying additional troops across the West Bank ahead of Friday prayers, often a gathering point for Palestinian demonstrations.

The ramming occurred in central Jerusalem shortly before 2:00 am (0000 GMT) where the soldiers had been marching, the army said, adding that one of them was "severely injured".

Public radio said they were new recruits on their way to an induction ceremony at Jerusalem's Western Wall, the holiest site where Jews can pray.

The attacker fled to the occupied West Bank but was arrested near the Gush Etzion settlement, Israeli police said.

An Israeli policeman inspects the scene of a Jerusalem car-ramming that wounded 14 Israelis, most of them soldiers
An Israeli policeman inspects the scene of a Jerusalem car-ramming that wounded 14 Israelis, most of them soldiers AFP / OREN BEN HAKOON

Prior to the arrest,

Israeli Prime Minister Benjamin Netanyahu made a visit to near the settlement and pledged a firm response.

"Terrorism will not defeat us; we will win!," he said

It was the most serious escalation in violence since US President Donald Trump revealed his peace plan on January 28.

Relatives mourn Palestinian teenager Mohammed al-Haddad, killed by Israeli fire during clashes in the flashpoint West Bank city of Hebron on Wednesday
Relatives mourn Palestinian teenager Mohammed al-Haddad, killed by Israeli fire during clashes in the flashpoint West Bank city of Hebron on Wednesday AFP / HAZEM BADER

A spokesman for Palestinian president Mahmud Abbas blamed Trump's peace proposal for the unrest.

"It was the deal of the century that created this atmosphere of escalation and tension," Nabil Abu Rudeinah said.

An armed supporter of Palestinian president Mahmud Abbas's Fatah movement fires his rifle during the funeral of 19-year-old Yazan Abu Tabikh, killed during an Israeli raid on the northern West Bank town of Jenin
An armed supporter of Palestinian president Mahmud Abbas's Fatah movement fires his rifle during the funeral of 19-year-old Yazan Abu Tabikh, killed during an Israeli raid on the northern West Bank town of Jenin AFP / Jaafar ASHTIYEH

Netanyahu hit back, directly addressing Abbas and accusing him of stoking violence.

"This will bring you nothing -- neither the stabbings, car rammings... or incitement to violence. We will do whatever it takes to keep us safe."

The Islamist Hamas movement, which controls the Gaza Strip and has fought three wars with Israel, hailed the car-ramming as a "practical response" to Trump's plan, but stopped short of claiming responsibility.

Rightwinger Netanyahu is facing an election on March 2 and his main rival also pledged a tough response to the attack.

An Israeli border guard aims his rifle towards Palestinian protesters during a raid near the West Bank town of Bethlehem
An Israeli border guard aims his rifle towards Palestinian protesters during a raid near the West Bank town of Bethlehem AFP / Musa Al SHAER

"We will settle the score with anyone trying to do us harm," centrist Benny Gantz, himself a former military general, said in a statement.

Trump's plan unilaterally gives Israel most of what it has sought in previous negotiations including an "undivided capital" in Jerusalem.

The plan angered Palestinians, whose leaders called for street protests over what they saw as its pro-Israel bias.

Trump's adviser and son-in-law Jared Kushner was scheduled to meet UN Security Council members on Thursday to present the plan, which he drew up.

Abbas is due at the UN next week to express opposition to the US initiative.

While the initial Palestinian response to the plan saw little violence, tensions have soared in recent days.

In the northern West Bank town of Jenin on Thursday, Israeli forces shot dead two people -- 19-year-old Yazan Abu Tabikh and Palestinian policeman Tareq Badwan.

The Israeli army said it had gone to the area to demolish the home of a Palestinian involved in the killing of a Jewish settler in 2018.

Troops then shot at Palestinians who had "hurled explosive devices and fired towards them", the army said.

Palestinian security sources said that Abu Tabikh was among the protesters when he was killed, but Badwan was in the courtyard of a police station close to the clashes when he was hit.

Israeli army spokesman Lieutenant Colonel Jonathan Conricus told reporters troops had shot a member of the Palestinian security forces and the army was investigating.

Separately a man opened fire on Israeli forces near the Al-Aqsa Mosque in Jerusalem's Old City, with forces responding by shooting him dead.

Police identified the gunman as an Arab resident of northern Israel who recently converted to Islam and is known to authorities over previous crimes.

The army said that it had decided to "reinforce Judea and Samaria Division with additional combat troops", using the biblical terms for the West Bank.

In the Gaza Strip, Israeli aircraft struck Hamas positions early Thursday, after Palestinians fired rockets or mortar rounds at Israel and launched incendiary balloons.

Since Trump's plan was announced, there has been almost daily fire from Gaza into southern Israel, drawing Israeli retaliation.

There have been no reported casualties.