Chip equipment maker Applied Materials
The $63-per-share deal represents a 55 percent premium to Varian stock's closing price on Tuesday.
The deal is expected to add to Applied Materials' adjusted earnings in the first year, it said.
Varian is a supplier of ion implantation equipment used by chipmakers around the world.
Varian shares closed at $40.55 on Tuesday on Nasdaq. (Reporting by Himank Sharma in Bangalore; Editing by Gopakumar Warrier)