Canadian Solar, Walgreen, Coach, Spectrum Pharmaceuticals, ASM International, Mellanox Technologies, AIXTRON SE and Herbalife Ltd. are among the companies whose shares are moving in the pre-market trading Wednesday.

Gainers

Canadian Solar Inc. (NASDAQ:CSIQ) stock surged 3.46 percent to $3.59 in pre-market trading. The company stock climbed more than 10 percent in regular trading Tuesday.

Walgreen Co. (NYSE:WAG) stock gained 1.44 percent to $41.63 in pre-market trading. The stock has a 52-week low of $28.53, a 52-week high of $42.00 and $38.79 billion in market capitalization.

Coach, Inc. (NYSE:COH) stock advanced 1 percent to $49.30 in pre-market trading. The stock has a 52-week low of $45.87, a 52-week high of $79.70 and $13.71 billion in market capitalization.

Losers

Spectrum Pharmaceuticals, Inc. (NASDAQ:SPPI) stock tumbled 40.47 percent to $7.40 in pre-market trading as its full year sales forecast fell short of expectations. The company expects full year 2013 revenues to be in a range of $160 million to $180 million, well below analysts’ estimate of full year revenue of $297 million.

ASM International N.V. (NASDAQ:ASMI) stock plunged 6.52 percent to $37.69 in pre-market trading. The stock has a 52-week low of $31.02, a 52-week high of $40.96 and $2.54 billion in market capitalization.

Mellanox Technologies, Ltd. (NASDAQ:MLNX) stock plunged 2.56 percent to $63.87 in pre-market trading. The company stock climbed nearly 14 percent in regular trading Tuesday after analysts’ at Lazard Capital raised their price target on shares of Mellanox to $69.00.

AIXTRON SE (NASDAQ:AIXG) stock declined 2.19 percent to $13.87 in pre-market trading. The stock has a 52-week low of $11.21, a 52-week high of $19.44 and $1.43 billion in market capitalization.

Herbalife Ltd. (NYSE:HLF) stock declined 1.73 percent to $39.68 in pre-market trading. The stock has a 52-week low of $24.24, a 52-week high of $73.00 and $4.16 billion in market capitalization.