The top after-market Nasdaq gainers Thursday were Anacor Pharmaceuticals Inc, James River Coal Company, Micron Technology Inc, and DryShips Inc, while the top after-market Nasdaq losers were TIBCO Software Inc, Tech Data Corp, Senomyx Inc, Monster Beverage Corp. and 8x8 Inc.

Gainers

Anacor Pharmaceuticals Inc. ( NASDAQ:ANAC) shares surged 5.37 percent to $5.10 in post-market trading. The company announced Thursday, positive results from a Phase 2 trial of its topical boron-based phosphodiesterase-4 (PDE-4) inhibitor, AN2728. The study included 86 adolescents (in the age group of 12-17 years) with mild-to-moderate atopic dermatitis, a chronic rash, which predominantly affects children.

James River Coal Company (NASDAQ:JRCC) shares advanced 4.52 percent to $2.08 in post-market trading.  The company shares lost over 5 percent in regular trading Thursday.

Micron Technology Inc. (NASDAQ:MU) shares climbed 3.42 percent to $9.38 in post-market trading. The company reported a net loss of $286 million or $0.28 per share for the fiscal second quarter ended Feb. 28. The company’s revenue rose to $2.1 billion from $2.0 billion, a year ago. Analysts on an average expected quarterly revenue of $1.922 billion.

DryShips Inc. (NASDAQ:DRYS) shares gained 1.42 percent to $15.75 in post-market trading. The company shares gained Thursday in line with other shipping stocks, which rose owing to better economic data from China. The company shares surged about 9 percent in regular trading Thursday.

Losers

TIBCO Software Inc. (NASDAQ:TIBX) shares plunged 15.19 percent to $19.65 in post-market trading. The company’s shares declined after it reported revenues that missed analysts' estimate for the third consecutive quarter and a profit in line with Wall Street's reduced expectations. Excluding items, earnings were 18 cents per share on revenues of $237.8 million. Analysts on an average had expected adjusted earnings of 18 cents per share on revenues of $242.5 million.

Tech Data Corp. (NASDAQ:TECD) shares dropped 9.18 percent to $45.00 in post-market trading. Block & Leviton LLP, a Boston-based law firm representing investors is investigating possible securities laws violations by Tech Data Corporation following the company's announcement that "investors should no longer rely upon the company's previously released financial statements."

Senomyx Inc. (NASDAQ:SNMX) shares slumped 7.89 percent to $2.10 in post-market trading. The company stock has a 52-week trading average of $1.53-$3.10 and a market capitalization of $91.43 million.

Monster Beverage Corporation (NASDAQ:MNST) shares fell 3.18 percent to $48.75 in post-market trading. The company stock declined following findings from a study that were presented at the American Heart Association meeting in New Orleans, which suggest that energy drinks may boost blood pressure and lead to an erratic heartbeat.

8x8 Inc. (NASDAQ:EGHT) shares dropped 3.03 percent to $6.73 in post-market trading.  The company stock has a 52-week trading average of $3.76-$7.95 and a market capitalization of $498.62 million.