The top after-market Nasdaq gainers Tuesday were ArQule Inc, Scientific Games Corp, Halozyme Pharmaceuticals Inc, XenoPort and STEC Inc. The top after-market Nasdaq losers were Spectrum Pharmaceuticals Inc, Velti Inc, Kratos Defense & Security Solutions and Move Inc.

Gainers

ArQule Inc (NASDAQ:ARQL) shares climbed 7.60 percent to $2.78 in post-market trading. The company shares have a 52-week trading range of $1.98-$8.32 and a market capitalization of $160.84 million.

Scientific Games Corp (NASDAQ:SGMS) shares rose 7.22 percent to $8.87 in post-market trading. The company shares lost 6.87 percent in regular trading Tuesday. The company shares have a 52-week trading range of $5.53-$12.29 and a market capitalization of $703.5 million.

Halozyme Pharmaceuticals Inc (NASDAQ:HALO) shares advanced 5.99 percent to $6.04 in post-market trading. The company shares lost 5.79 percent in regular trading Tuesday. The company shares have a 52-week trading range of $3.86-$13.50 and a market capitalization of $640.26 million.

XenoPort Inc (NASDAQ:XNPT) shares gained 5.31 percent to $8.14 in post-market trading. The company shares lost 10.07 percent in regular trading Tuesday. The company shares have a 52-week trading range of $3.88-$12.98 and a market capitalization of $331.87 million.

STEC Inc (NASDAQ:STEC) shares surged 4.34 percent to $5.29 in post-market trading. The company shares have a 52-week trading range of $3.95-$9.80 and a market capitalization of $236.90 billion.

Losers

Spectrum Pharmaceuticals Inc (NASDAQ:SPPI) shares plunged 40.47 percent to $7.40 in post-market trading. The company Tuesday announced a steep 40 percent guidance reduction for 2013, setting a revenue target between $160 million to $180 million, compared to analysts’ estimate of $300 million. 

Velti Plc (NASDAQ:VELT) shares declined 24.12 percent to $2.36 in post-market trading. Velti Plc reported adjusted EPS of $0.39, missing the mean analysts' estimate of $0.59. It reported revenues of $97.5 million from the year earlier quarter missing the average revenue estimate of $106 million. The company shares have a 52-week trading range of $2.93-$14.65 and a market capitalization of $202.14 million.

Kratos Defense & Security Solutions Inc (NASDAQ:KTOS) shares lost 16.29 percent to $3.75 in post-market trading. The company reported adjusted EPS of $0.15, missing the mean analysts' estimate of $0.07. It reported revenues of $263.6 million from the year earlier quarter beating the average revenue estimate of $262.28. The company stock has a 52-week trading range of $4.08-$6.36 and a market capitalization of $253.59 million.

Move Inc (NASDAQ:MOVE) shares dropped 6.37 percent to $10.51 in post-market trading. The shares gained 6.65 percent in regular trading. The company shares have a 52-week trading range of $6.92-$ 11.25 and a market capitalization of $444.69 million.