The top after-market Nasdaq gainers Wednesday were Complete Genomics Inc, Allscripts Healthcare Solutions Inc, Silicon Graphics International Corp, Salix Pharmaceuticals Ltd and Photronics Inc.

The top after-market Nasdaq losers were Boingo Wireless Inc, SunPower Corporation, Monster Beverage Corporation, Career Education Corporation and Alaska Communications Systems Group Inc.

Gainers

Complete Genomics Inc (GNOM) shares climbed 9.79 percent to $2.58 in after-hours trading Wednesday. The company reported the second quarter revenue at $8.7 million, compared to the $5.9 million and the loss of $0.55 per share versus $0.56 per share loss in the same period a year ago. 

The shares of Allscripts Healthcare Solutions Inc (MDRX) rose 7.60 percent in the post-market to close at $10.33. The company reported Wednesday an EPS of $0.16 for the quarter, lower than the consensus estimate of $0.18. The company's quarterly revenue was up 3.7 percent on a year-over-year basis. The company lifted its full-year adjusted earnings' outlook to a range of $0.77 to $0.83 per share as compared to the previous guidance range of $0.74 to $0.80 per share.

Silicon Graphics International Corp (SGI) shares advanced 7.48 percent to $7.33 in the post-market trading. The company announced Wednesday the non-GAAP fourth-quarter loss of 10 cents per share beating analysts' expectations of a loss of 43 cents per share.

Salix Pharmaceuticals Ltd (SLXP) shares gained 6.69 percent and reached $48.00 in after-hours trading. The company lifted its estimates for the fiscal 2012. The total company product revenue remains at $735 million with an increased adjusted net income of $183 million or $2.86 per share. Analysts were expecting the company to report revenues of $742 million, a net income of $173 million and an EPS of $2.65.

Photronics (PLAB) shares surged 6.23 percent to $6.14 in after-hours trading Wednesday.  

Losers

Boingo Wireless Inc (WIFI) shares slumped 13.33 percent to $7.80 in post-market trading Wednesday. The company announced, Wednesday, its second quarter earnings per share and revenue that were below analysts' expectations. It expects the revenue to be in the range of $25.5-$26.5 million, the adjusted EBITDA to be in the range of $7.5-$8.5 million and the net income to be in the range of $2.2-$2.7 million or $0.05 to $0.06 per diluted share, against the analysts' estimate of revenues of $28.8 million, the EBITDA of $9.6 and the net income of $3.1 and the EPS of $0.08 for the third quarter of 2012.

SunPower Corporation (SPWR) shares plunged 12.58 percent to $4.10 in the post-market trading. The company announced quarter results beating the analysts' expectations, but its third quarter results were below the market expectation. It expects consolidated non-GAAP revenue of $550 million to $625 million, earnings per diluted share loss of ($0.20) to ($0.05). On a GAAP basis, the company expects a revenue of $545 million to $620 million, a net loss per diluted share of ($0.25) to ($0.10), while analysts were expecting the company to report revenues of $730 million and an EPS of 0.01 for the third quarter of 2012.

Monster Beverage Corporation (MNST) shares lost 9.69 percent in after-hours trading to reach $61.20. The company announced its second quarter profit of $109.8 million or 59 cents per share that fell short of the analysts' estimate of 61 cents per share. The revenue increased 28.2 percent to $592.6 million, missing the consensus estimate of $596.1 million.

Career Education Corporation (CECO) shares dropped 7.30 percent to $3.43 in after-hours trading. Barclays Capital is cutting Career Education Corp. FY13 estimate to -0.22 from 0.12. The company's shares had gained 7.87 percent in regular trading Wednesday.

Alaska Communications Systems Group Inc (ALSK) shares lost 5.99 percent to $2.04 in after-market trading Wednesday.