The top after-market Nasdaq gainers Tuesday were Vitesse Semiconductor Corporation, CSG Systems International Inc, Express Scripts Holding Company, Interval Leisure Group Inc and Ctrip.com International Ltd.

The top after-market Nasdaq losers were priceline.com Incorporated, Santarus Inc, Zillow Inc, XOMA Corporation and Horizon Technology Finance Corporation.

Gainers

Vitesse Semiconductor Corporation (VTSS) shares climbed 9.59 percent to $2.40 in after-hours trading Tuesday. The company reported a third quarter income of $0.00 per share, better than the analysts' expectation of a loss of $0.03 per share.  The revenue for the quarter came in at $30.3 million versus the consensus estimate of $29.65 million.

The shares of CSG Systems International Inc (CSGS) rose 7.58 percent in the post-market to close at $19.15. The company reported second quarter EPS of 56 cents, better than the analysts' estimate of 45 cents. The revenue for the quarter stood at $183.9 million versus the consensus estimate of $180.75 million.  The company also gave a strong revenue forecast of $722-$747 million versus a prior guidance of $715-$740 million and the analysts' expectation of $730.55 million for the FY2012. 

Express Scripts Holding Company (ESRX) shares advanced 7.02 percent to $59.95 in the post-market trading. The company reported a second quarter EPS of $0.88, better than the market estimate of $0.82. The revenue for the quarter came in at $27.7 billion, up 143.8 percent from the same quarter a year ago and against the analysts' estimate of $26.62 billion.

Interval Leisure Group Inc (IILG) shares gained 6.26 percent and reached $20.70 in after-hours trading. The company reported second quarter earnings per share of $0.18 versus $0.13 in the prior year, an increase of 38.5 percent. The Group announced that its Board of Directors has declared a $0.10 per share dividend, payable September 20, 2012 to shareholders of record on Sept. 6, 2012.

Ctrip.com International Ltd (CTRP) shares surged 5.52 percent to $14.34 in after-hours trading Tuesday.  

Losers

Priceline.com Incorporated (PCLN) shares slumped 14.83 percent to $579.00 in the post-market trading Tuesday. The company reported second quarter results beating analysts' expectations but gave a disappointing third quarter forecast.  Excluding items, the earnings for the second quarter were at $7.85 per share beating analysts' expectations for $7.37 per share. The company gave the earnings expectations for the Q3 with a range of $11.10 to $12.10 per share excluding items, which is below analysts' expectations of $12.79.    

Santarus Inc (SNTS) shares plunged 11.08 percent to $6.50 in the post-market trading. The company reported a second quarter EPS of $0.05, less than the consensus estimate of $0.08 by $0.03. The company announced that for fiscal 2012, it expects total revenues of approximately $200 million, net income of approximately $8-$11 million and adjusted EBITDA of approximately $24-$29 million versus analysts expectation of revenue at $199 million, net income of $11 million and EBITDA of $24 million for fiscal 2012.  

Zillow Inc (Z) shares lost 9.60 percent in after-hours trading to reach $37.75. The company reported second quarter EPS of 4 cents Tuesday, compared to the prior year's break-even results. The consensus estimate was for EPS of 4 cents. The company's quarterly profit fell modestly as the real estate website accounted for costs related to its acquisition of software start-up RentJuice Corp, Reuters reported.

XOMA Corporation (XOMA) shares dropped 9.46 percent to $2.87 in after-hours trading. The company reported second quarter net loss $16.2 million or $0.24 per share versus the loss $8.1 million or $0.27 per share from the same period last year.

Jive Software Inc. shares dropped 9.01 percent to $17.67 in after-market trading after the company gave a weak full-year guidance that fell below analysts' expectations.