Delta, US Airways, American Airlines, Midwest and United, are kicking off a two-day sale to and from more than 60 cities in the United States for travel through November 16, 2010, Bestfares.com reports.

The sale for airplane tickets ends at 11:59 p.m. EST, Thursday, the site notes.

Continental Airlines is also offering sales through June 12, 2010, according to the site which tracks ticket prices and deals.

Roundtrip airfares were selling for as low as $78 from New York City to Pittsburgh, the site noted. A roundtrip from Orlando to Chicago, Dallas or St. Louis sold for $168.

Some of the major U.S. cities in the sale include: Atlanta, Baltimore, Chicago, Dallas, Detroit, Houston, Las Vegas, Los Angeles, Miami, New York City, Orlando, Phoenix, San Francisco, Seattle, Washington D.C. among others.

There are some restrictions. According to the report: a 10 day advance purchase is required, there are about 28 blackout dates and travel is valid everyday except Fridays and Sundays.

Also, flights departing or arriving in Florida are only valid between April 6 and November 16, 2010.

Visit Bestfares.com to find the bargains.

American Airlines Sale