Russell Wilson Seattle Seahawks
The Seahawks are the week's biggest favorites, once again. Reuters

Two of the NFL’s brightest young stars lead their teams in arguably Week Five’s top game on Sunday as the Indianapolis Colts welcome the Seattle Seahawks to Lucas Oil Stadium.

Quarterbacks Andrew Luck and Russell Wilson each led their teams to the playoffs in their rookie seasons a year ago, and bragging rights could be on the line.

After four games, both have pleaded their cases for who is the better quarterback. Comparing their stats, Luck edges Wilson out in passing yardage 915 to 787, but Wilson has six passing touchdowns to Luck’s five, and four more points on his passer rating. However, Luck makes up the difference with two rushing scores.

Wilson and the Seahawks are one of the five remaining undefeated teams in the NFL, despite a wild finish to last week’s 23-20 overtime victory over the Houston Texans.

Running back Marshawn Lynch scored his third touchdown on the season on a three-yard dash, and corner Richard Sherman ran his interception back 58 yards for a touchdown while the Seattle defense blanked Houston for the entire second half.

Sherman and safety Earl Thomas anchor the NFL’s fourth secondary, giving a pittance of 191.1.3 passing yards a game.

The Colts and Luck are now atop the AFC South thanks to Seattle’s toppling of Houston, and their 37-3 victory over Jacksonville gives them an inside track to the franchise’s first division title in three years. Luck threw both of his touchdowns in the third quarter to tight end Coby Fleener and receiver Reggie Wayne, and Indianapolis had the game at hand with a 31 point lead heading into the final quarter.

Trent Richardson has been more than a welcome addition since Indianapolis trade for him before Week Three, scoring a touchdown in each of his first two games.

Luck does have one leg over Wilson, linebacker Robert Mathis, who’s tied for first in the NFL with 7.5 sacks through four games.

However there might be less of a lane for Mathis to push through with defensive end Ricky Jean-Francois out in Week Five. Seattle could also miss Sherman’s immediate backup Jeremy Lane, who's listed as doubtful.

Coverage of the game starts at 1 p.m. ET and will be broadcast by FOX, or or watch a live online stream by purchasing NFL Game Access here.

Betting Odds: Seattle is favored by 3 points.

Over/Under: 43.5 points.

Prediction: Indianapolis 30, Seattle 27