Police are frantically searching for Lisa Irwin, a ten month-old infant who is believed to have been kidnapped from her Kansas City, Mo. , bedroom sometime late Monday night or Tuesday morning.

Lisa's parents last saw their daughter at about 10:30 p.m. Monday, and called to report her missing at about 4 a.m. Tuesday.

They saw the window and the screen appeared that it was tampered with, Officer Darin Snapp, public information officer for the Kansas City Police, told ABC News.

I realize that some of these Amber Alerts involve parents or parental abductions, but we have both the parents here, police Sgt. Stacey Graves told MSNBC.  So that puts us on a little higher state of alert.

Police are urging people with any possible information to TIPS Hotline at 816-474-8477, or 911.

Police said Lisa has blue eyes and blond hair. She is 30 inches tall and weighs 26 to 30 pounds. The baby was last seen wearing purple shorts and a purple shirt with white kittens on it. She has a cold with a cough, a small bug bite under her left ear, a beauty mark on her outer right thigh, and two bottom teeth.

KMBC's Peggy Breit reported that the girl's mother was taken in a police cruiser to police headquarters for an interview. Police had said earlier that both parents were fully cooperative with the investigation.

KMBC's Micheal Mahoney reported that authorities concentrated some of their search efforts in a wooded area to the west of home. Mahoney added that the home is on a windy road that is unlikely to have been accessed by a random pedestrian.

Police were canvasing the neighborhood on Tuesday and interviewing possible witnesses.

We are interviewing family and friends just to eliminate everyone's that close to the family as suspects, Snapp told ABC News, adding that the area is a middle class, very quiet neighborhood.