Both Isco and Joaquin are set to return to Malaga’s starting lineup after being rested in the weekend draw with Real Valladolid. The attacking pair are likely to be crucial in helping to overturn the Spanish side’s 1-0 deficit from the first leg in Porto.
Julio Baptista is also available having recovered from a hamstring injury. The Brazilian started the match in Portugal three weeks ago in one of his first appearances after a long spell out with injury. It is likely that the attacking midfielder will have to make do with a place on the bench on Tuesday, however.
Lucas Piazon has impressed since joining on loan from Chelsea in January and the 19-year-old could start on the left of a line of three, alongside Isco and Joaquin, behind either Roque Santa Cruz or Javier Saviola.
The two South American strikers began in tandem, but given the threat of an away goal, coach Manuel Pellegrini is likely to start with just one against Porto. The pair have been alternated for much of the season, though Santa Cruz got the nod in the first leg.
Porto have received a significant boost with the news that their goal-scorer in the first leg, Joao Moutinho is expected to be fit after missing the past two games with a thigh injury. Also likely to start having missed the last two games is central defender Eliaquim Mangala.
Having only appeared as a substitute in the first leg as he continued his return to fitness, Porto will also have key attacking threat James Rodriguez back in the starting lineup. The exciting 21-year-old should form an attacking trident also featuring fellow-Colombian Jackson Martinez and Silvestre Varela.
D: Gamez, Demichelis, Weligton, Antunes
M: Camacho, Toulalan
Joaquin, Isco, Piazon
F: Santa Cruz
D: Danilo, Otamendi, Mangala, Alex Sandro
M: Gonzalez, Fernando, Moutinho,
F: Rodriguez, Martinez, Varela
You can get a full preview and prediction of the encounter here.
Where to watch: the second leg of the Champions League last-16 tie will kick-off from La Roasaleda at 3.45 p.m. ET. Coverage will be provided by Fox Soccer Plus, with a live stream available on Fox Soccer 2Go.