Marge Simpson is seen on the cover of the November issue of Playboy magazine in this handout released to Reuters on October 9, 2009. REUTERS/Playboy Magazine/Handout

D'oh! doesn't even start to cover it.

Marge Simpson -- the blue beehived matriarch of America's most loved dysfunctional family - is Playboy magazine's November cover, the magazine said on Friday.

Simpson, tastefully concealing her assets behind a signature Playboy Bunny chair, is the first cartoon character ever to front the glossy adult magazine, joining the ranks of sex symbols like Marilyn Monroe and Cindy Crawford.

Playboy said the cover celebrates the 20th anniversary of the The Simpsons. Homer, Marge, Bart, Lisa and Maggie have already been honored this year with a set of U.S. postal stamps.

The magazine promises a story inside called The Devil in Marge Simpson and another three pages of pictures.

Animated series The Simpsons debuted in December 1989 with a Christmas-themed episode called Simpsons Roasting on an Open Fire. It has won 24 primetime Emmys and was renewed by Fox television earlier this year for two more seasons.

The Simpsons began its 21st season last month, putting it on track to become the longest-running primetime series on U.S. television.

The November issue of Playboy hits newsstands on October 16.