Oregon Michigan State
Running back Royce Freeman runs for a first down during the third quarter of Oregon's game against Michigan State at Autzen Stadium on Sept. 6, 2014 in Eugene, Oregon. Getty

Michigan State’s only missteps last season came against the best teams in college football, suffering their only two losses to Ohio State and Oregon. With the Spartans ranked No.5 in the second week of the 2015 season, they have a strong chance to make the second ever College Football Playoff, and it all starts with a rematch against the Ducks.

After losing Marcus Mariota to the NFL, Oregon ranks No.7 in the AP Top 25 poll. They remain one of the sport’s top teams, but they are the underdogs in this year’s matchup with Michigan State.

If the Spartans want to make the postseason, they might have to beat both Oregon and Ohio State. After falling short against both teams last season, Michigan State is ready for the challenge this year.

“Seeing the two teams you lost to playing for the national championship really wasn’t the best thing,” Michigan State quarterback Connor Cook said, via Sports Illustrated. “So we emphasized that throughout the whole off-season, whether it was one more rep, an extra workout, whatever it is, dedicating that to a loss we had last year when we were so close.”

Oregon has hopes of returning to the playoffs after being upset in last season’s title game, where they lost to Ohio State. They are 3.5-point underdogs in their visit to East Lansing, Michigan. The Ducks were favored in all of their games last season.

Michigan State vs. Oregon is one of just three games on Saturday that features two ranked teams. No.14 LSU visits Mississippi State and No.19 Oklahoma visits No.23 Tennessee.

Start Time: 8 p.m. ET

TV Channel: ABC

Online Stream: WatchESPN