Stand-up comedian Patrice O'Neal died on Tuesday from complications of a stroke at age of 41.

O'Neal died on Tuesday at the age of 41. He suffered a stroke last month, his agent said.

It is with terrible sadness we must report that Patrice O'Neal has passed away this morning...due to the complications of the stroke he suffered on October 19, Matt Frost, O'Neal's agent, stated.

Many of us have lost a close and loved friend; all of us have lost a true comic genius, Frost added.

Yes it's true that our pal Patrice O'Neal has passed away. The funniest and best thinker I've known. PERIOD, the Sirius XM hosts tweeted.

O'Neal, who was a frequent guest on the Opie & Anthony radio show on Sirius XM, appeared on Conan O'Brien's and David Letterman's TV shows.

According to Frost, O'Neal died before his mother Georgia. He is survived by his wife, Vondecarlo, his step daughter Aymilyon and sister Zinder.

The family wishes to thank all of the fans and friends who have expressed an outpouring of love and support for Patrice these past weeks. We ask that you please respect the family's request for privacy at this difficult time, a statement read.

The tributes for the comedian are pouring in.

The entertainment world as well as the world at large lost a brilliant man, Charlie Sheen tweeted on Tuesday.

Patrice had that rare `light' around him and inside of him. I only knew him for the few days leading up the Roast. Yet I will forever be inspired by his nobility, his grace and his epic talent. My tears today are for the tremendous loss to his true friends and loving family, he added.

RIP Patrice O'Neal. You made us laugh til we cried, tweeted comedian Sarah Silverman.

Just heard. Goodnight brother. Damn. Just ridiculous. Terrible. Beyond sad, actor Jay Mohr tweeted.