Pluristem Therapeutics Inc, Telefonica S.A, ArcelorMittal, International Business Machines Corp, Intel Corp, Diageo plc, Alpha Natural Resources and Barclays Plc. are among the companies whose shares are moving in pre-market trading Wednesday.

Pluristem Therapeutics Inc. (PSTI) stock surged 4.80 percent to $4.15 in pre-market trading. The company announced that a reduction of fibrotic processes has been demonstrated in preclinical and in vitro studies using Pluristem's Placental eXpanded (PLX) cells.

Telefonica S.A. (TEF) stock surged 3.08 percent to $14.07 in pre-market trading. The company said on Tuesday that it plans to list 23 percent of its O2-branded German unit at between 5.25 euros ($6.79) and 6.50 euros per share, valuing the stake at about 1.52 billion euros, Reuters reported.

ArcelorMittal (MT) stock surged 3.02 percent to $16.05 in pre-market trading. The stock has a 52-week low of $13.28, a 52-week high of $23.62 and $24.14 billion in market capitalization.

International Business Machines Corp. (IBM) stock plunged 3.48 percent to $203.66 in pre-market trading.  The company reported third quarter net income of $3.82 billion or $3.33 per share compared to $3.84 billion or $3.19 per share in the same period last year. Revenue declined 5 percent to $24.7 billion. For the fiscal year 2012, IBM reiterated its operating earnings per share expectation of at least $15.10 while analysts currently expect $15.14 per share.

Intel Corp. (INTC) stock declined 2.91 percent to $21.70 in pre-market trading. Its third quarter net profit declined to $2.97 billion or $0.58 per share from $3.47 billion or $0.65 per share in the same period last year. Adjusted net income was $3.12 billion or $0.60 per share, down from $3.63 billion or $0.68 per share last year but topped Reuters estimation of $0.50 per share. Intel forecasts fourth-quarter revenue will range between $13.1 billion and $14.1 billion compared to analysts’ estimate of $13.78 billion.

Diageo plc (DEO) stock declined 2.19 percent to $112.61 in post-market trading. The stock has a 52-week low of $79.39, a 52-week high of $116.96 and $72.21 billion in market capitalization.

Alpha Natural Resources, Inc. (ANR) stock declined 1.75 percent to $8.40 in pre-market trading. The company stock was downgraded to a “neutral” from “buy” rating at Nomura Tuesday.

Barclays Plc. (BCS) stock fell 1.39 percent to $15.58 in pre-market trading. The stock has a 52-week low of $9.20, a 52-week high of $16.41 and $48.33 billion in market capitalization.