The Kansas City Chiefs were one of the few teams that were able to defeat the Seattle Seahawks in last year’s regular season, and they’ll try to do the same in Friday night’s exhibition game. The two teams are set to meet at Arrowhead Stadium in Week 2 of the 2015 NFL preseason.

Kansas City might have trouble protecting quarterback Alex Smith the way they’d like. A knee injury will force right tackle Jeff Allen to miss the contest, and left tackle Eric Fisher will sit with a high ankle sprain.

"I think we’ll be OK,” head coach Andy Reid told reporters on Wednesday. “We’ve got [Paul] Fanaika and Jarrod Pughsley who can go in there and play at the tackle spot and the rest of the guys you saw in there, so the right tackle spot would be the place where we would need to put somebody in.”

Six other Chiefs have been ruled out of Friday’s game. Tight end Demetrius Harris, quarterback Tyler Bray, inside linebacker Justin March, wide receiver Junior Hemingway (hip sprain), nose tackle Dontari Poe and offensive tackle Tavon Rooks will all miss the game with injuries.

Just like they did in their preseason opener against the Denver Broncos, the Seahawks will play without their Pro Bowl safeties. Kam Chancellor continues to hold out, looking for his contract to be restructured, and he could even stay off the field once the regular season begins. Earl Thomas was limited at practice this week as he recovers from his offseason shoulder surgery. Meanwhile, backup quarterback Tarvaris Jackson's ankle is "legitimately sprained," according to head coach Pete Carroll. The team hopes the 32-year-old will only be out a couple of weeks.

Russell Wilson, who recently signed an $87.6 million contract extension, hopes to have more time to throw than last week. The starting quarterback was only able to attempt one pass against Denver, getting sacked twice. In all, the Seahawks allowed all three quarterbacks that played to get sacked seven times.

Seattle’s rushing attack didn’t have much success against a struggling offensive line either. The team totaled 89 yards on 24 attempts without starting running back Marshawn Lynch. If “Beast Mode” does see some time on the field, it won’t likely be much.

Lynch had his second-highest rushing total of last season against the Chiefs, totaling 124 yards on 24 carries. But Jamaal Charles was even better, going for 159 yards on 20 attempts in a 24-20 win. Charles didn’t carry the ball in Kansas City’s 34-19 preseason opener win over the Arizona Cardinals.

Start Time: 8 p.m. ET

TV Channel: NFL Network

Online Stream:

Point Spread: Chiefs -3

Over/Under: 40.5 points