Stock index futures pointed to a weaker open on Wall Street on Wednesday, with futures for the S&P 500, the Dow Jones and the Nasdaq 100 all down 0.4 percent.

The Labor Department was set to release the May consumer price index at 1230 GMT (8:30 a.m. ET). Economists in a Reuters survey expected a 0.1 percent rise, compared with April's 0.4 percent increase.

The Mortgage Bankers Association will release its Weekly Mortgage Market Index for the week ended June 10 at 1100 GMT. The index read 517.5 in the prior week when the refinancing index was 2,475.7.

Resource-related stocks will be in focus as crude oil fell as rising gasoline stockpiles in top consumer the United States signaled fuel demand was stalling.

At 1230 GMT, the Labor Department issues Real Earnings for May. Economists expected real earnings to fall 0.2 percent versus an April drop of 0.3 percent.

Swiss Stock Exchange officials are probing Swiss medical device maker Synthes's unusual share spike before its takeover by Johnson & Johnson , the Wall Street Journal reported, citing people familiar with the matter.

The New York Federal Reserve releases its Empire State Manufacturing Survey for June at 1230 GMT. Economists expected a reading of 12.50, compared with 11.88 in May.

The Treasury Department issues at 1300 GMT net capital inflows and foreign treasury purchases for April. In March, net capital inflows were $116.0 billion and foreign net purchases of U.S. treasuries were $26.78 billion.

The Federal Reserve releases industrial production and capacity utilization data for May at 1315 GMT. Economists expected a 0.2 percent rise in production and a reading of 77.0 percent for capacity utilization.

Euro zone ministers failed to reach agreement on Tuesday on how private holders of Greek debt should share the costs of a new bailout, putting the onus on the leaders of Germany and France to forge a deal later this week.

The FTSEurofirst 300 <.FTEU3> index of top European shares was down 0.1 percent on concerns about Greece's debt situation, after rising 0.8 percent on Tuesday, buoyed by Chinese economic data.

On Tuesday, the Dow Jones industrial average <.DJI> gained 123.14 points, or 1.0 percent, to 12,076.11. The Standard & Poor's 500 Index <.SPX> rose 16.04 points, or 1.3 percent, to 1,287.87. The Nasdaq Composite Index <.IXIC> advanced 39.03 points, or 1.5 percent, to 2,678.72.

(Reporting by Atul Prakash; Editing by Dan Lalor)