Looks like Sam (Jared Padalecki) and Dean (Jensen Ackles) will be doing more than just singing lullabies to little Amara as Season 11 of “Supernatural” continues. In the anticipated premiere of the hit CW series, the Winchester brothers became surrogate fathers to a baby girl after the child’s father was infected with The Darkness.

When the primordial entity was released from its captivity – thanks to Rowena’s (Ruth Connell) spell – a sickness spread throughout Earth, contaminating hundreds of innocent people (including Sam), giving them a thirst for blood and a gruesome black veins. But the most shocking moment of episode 1, titled “Out of the Darkness, Into the Fire,” was when it was discovered that the adorable, parent-less baby was sporting the evil Mark of Cain. Yep, that’s right – Amara is a demon baby.

So, what does this mean for Sam and Dean? Will they be forced to kill the child for the sake of humanity – a topic they heavily addressed during the premiere? Or will they find a way to remove the mark from Amara?

The synopsis for episode 2, titled “Form and Void,” reveals that Dean will spend the upcoming episode attempting to get Jenna (Laci Mailey) and Amara to safety before returning to his brother’s side to save a town that has been “infected by a mysterious and deadly gas.”

But when Jenna’s life becomes at risk, she’ll call upon the eldest Winchester to help her. Will Dean choose to save Jenna over the town? In the premiere, Sam weighed that very option as he questioned their hunting mission.

“When did we forget how to do this?” he asked his brother. “Dean, if we don’t change, right now, all of our crap is just going to keep repeating ourselves… Saving people means all of the people, not just that baby, not just each other.”

But, according to the summary, Sam will go against his previous statement and urge his brother to help Jenna and the baby. Perhaps the reason for Sam's change of heart is because he’s slowly getting sicker and sicker with the gruesome disease and doesn’t want his brother to see the black veins forming on his neck.

Unfortunately for Sam, his solo journey will be harder than he thought when he’s forced to “handle the townspeople turned monsters” on his own.

“Supernatural” airs Wednesday nights at 9 p.m. EDT on The CW.