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The top pre-market NASDAQ Stock Market gainers are: Conns, Expedia, Curis, Seagate Technology, and NXP Semiconductors. The top pre-market NASDAQ Stock Market losers are: Hercules Offshore, Idenix Pharmaceuticals, Sangamo Biosciences, Qiao Xing Universal Resources, and Costco Wholesale.

The top after-market NASDAQ Stock Market gainers are: Expedia, Seagate Technology, Cutera, ShoreTel, and Select Comfort. The top after-market NASDAQ Stock Market losers are: Hercules Offshore, Idenix Pharmaceuticals, Sangamo Biosciences, PostRock Energy, and China-Biotics.

Shares of Cubist Pharmaceuticals Inc. (CBST) touched a new 52-week high of $30.02 on Wednesday morning. Optimer Pharmaceuticals Inc. (OPTR) said it has entered an exclusive two-year co-promotion agreement with Cubist to market Dificid in the U.S.

Police authorities in the small Californian town of Arroyo Grande have said an incident of cross burning is being investigated as a theft, arson and hate crime.

Oral arguments for the Myriad Genetics, Inc. appeals case is set to begin April 4 with a possible written decision in June 2011, RBC Capital Markets said.

The merger of T-Mobile USA with AT&T would be one of the biggest wireless mergers of the last several years, will probably go through despite increased scrutiny from regulators.

In an 8 minute video news report, former U.S. Prosecutor Richard Fine outlines his strategy to return integrity to the California Court system and the reasons why State Superior Court Judges cannot sit on cases where they have received money from parties who appear before them.

Foreign banks have not gotten the message when it comes to helping American clients avoid paying taxes, a top U.S. tax prosecutor said on Thursday.

An Apple executive accused of taking kickbacks to help suppliers secure favorable contracts has pled guilty to wire fraud, conspiracy and money laundering.

U.S. regulators' efforts to settle with banks over improper mortgage foreclosures are being hampered by infighting among the groups involved in the talks, and a settlement may take a while, according to sources familiar with the matter.

While most are against Apple's new subscription policy, a few have spoken out in favor of it.

The approval for Google’s acquisition of ITA Software for $700 million is still pending from the U.S. Justice Department, as it is considering if the deal will give Google influence over the entire online flight industry.

Three items totaling about $2.4 trillion combine for nearly two thirds of President Barack Obama's proposed $3.7 trillion 2012 fiscal year budget.

Daniel Patrick Boyd, a U.S. citizen and resident of North Carolina, has pleaded guilty in a federal court to charges of conspiracy to provide material support to terrorists and conspiracy to murder, kidnap, maim, and injure persons in a foreign country, the U.S. Department of Justice (DOJ) said.

U.S. President Barack Obama said on Tuesday Pakistan must respect the diplomatic immunity of a U.S. consular employee jailed for shooting dead two Pakistanis, in a case straining ties between the allies.

Arizona governor Gov. Jan Brewer is suing the U.S. Federal Government, saying it has failed to protect the state's citizens from the hazards of illegal immigration.

A investigation into allegations of insider trading in the hedge fund industry for the first time reached former employees of billionaire trader Steven A. Cohen's SAC Capital Advisors.

Wealthy tax evaders with assets stashed offshore can come clean with U.S. authorities under a new amnesty program with reduced penalties, the government said on Tuesday.

Chipotle Mexican Grill (CMG.N) has a lot going for it -- an upscale burrito concept, a hip and eco-friendly image, expansion plans galore and a 500 percent-plus stock price gain in just over two years.

Oakland officials have been warned by federal authorities not to allow large-scale marijuana farms in the city as it violates U.S. laws and could lead to a crackdown on the growers and their backers.

Colleen R. LaRose, a Pennsylvania woman also known as 'Jihad Jane,' has pleaded guilty to conspiring to murder a Swedish cartoonist, providing material support to terrorists, and other criminal charges

Pimps will traffic thousands of under-age prostitutes to Texas for Sunday's Super Bowl, hoping to do business with men arriving for the big game with money to burn, child rights advocates said.

Being the first of the social media websites to be blocked in Egypt amid anti-government protests, Twitter has churned out a blog on the importance of freedom of expression.

Defense contractor Lockheed Martin has agreed to pay the U.S. government $2 million to settle charges that it acted with others in knowingly violating the False Claims Act by rigging a contract at Stennis Space Center in Mississippi.

U.S. generic drug maker Mylan Inc has settled two U.S. patent disputes with global pharma giant Pfizer Inc, which will enable the former to sell the generic versions of cholesterol drug Lipitor and combination blood pressure and cholesterol treatment Caduet.

Will MTV's controversial teen-age based drama Skins be taken off air amid advertiser and ratings woes as well as ire from media watchdog group?

Convicted serial killer Rodney Alcala, aged 67, faces new charges of killing two New York women in 1970s.

Ahmed Khalfan Ghailani, who played a vital role in the 1998 al Qaeda bomb attacks on U.S. embassies in Kenya and Tanzania that killed 224 people including 12 Americans and wounded thousands of others, has been sentenced to life by a Manhattan federal court.

The Department of Justice was reprimanded today by the U.S. Congress for suggesting the necessity of the Internet Data Retention legislation, which if passed would require Internet Service Providers (ISPs) to preserve records of user activity longer, but failing to provide more details on how it could aid in criminal investigations.