European shares were trading largely mixed following Asian markets Tuesday, while U.S. stock futures pointed to a weak opening.

The FTSE 100 and France's CAC 400 traded largely flat but were pointing down. Shares in Germany's DAX dropped 0.34 percent while the pan-European Stoxx 600 traded flat too.

In the U.S., stock futures on the S&P 500, Dow Jones and Nasdaq were down between 0.15 percent to 0.21 percent after a strong showing in Monday trading on these exchanges. 

As the U.S. earnings season winds down, investors are looking to Friday's employment report, for clues as to whether the Federal Reserve will raise interest rates when it meets in December, according to Reuters.

In Asia, the Shanghai Composite Index ended down 0.25 percent, while Hong Kong's Hang Seng was up 0.89 percent. The Nasdaq-style Chinext Index was down 0.11 percent. India's BSE Sensex was up 0.12 percent at close following a volatile trading session while South Korea's Kospi was up 0.65 percent. Japan's benchmark Nikkei index was closed for trade due to a holiday.