Scroll down in this article to watch the actor round the bases and slide into home plate.
Murray, known for his roles in Caddyshack, Lost In Translation and the Ghostbusters films, is a Chicago native and threw out the first pitch Thursday to open up the baseball season for the Cubs.
Bill Murray has a passion for sports and lets out his humorous side as a staple of the PGA Pro-Am golf tournaments. He won the event last year with pro golfer D.A. Points.
Murray has entertained crowds with his zany attire and antics during the tournaments.
Unfortunately for Murray and Cubs fans everywhere, Chicago lost to the Nationals, 2-1.
![Pig's Head Prank In British Soccer Player Kenwyne Jones' Locker, Stoke City Club Launches Investigation [PHOTO]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_thumbnail/public/2013/05/17/pigs-head.jpg "Pig's Head Prank In British Soccer Player Kenwyne Jones' Locker, Stoke City Club Launches Investigation [PHOTO]")
!['Grand Theft Auto 5': New Screenshots Released [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_thumbnail/public/2013/04/02/grand-theft-auto-v.jpg "'Grand Theft Auto 5': New Screenshots Released [PHOTOS]")
![Fort Worth Texas Tornadoes Claim 6 Lives: Pictures And Videos During The Storm And Its Aftermath [PHOTOS/VIDEO]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/16/tornado.PNG "Fort Worth Texas Tornadoes Claim 6 Lives: Pictures And Videos During The Storm And Its Aftermath [PHOTOS/VIDEO]")
![Introducing Skywhale: Canberra, Australia’s Controversial $300K Centenary Balloon [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_multimedia/public/2013/05/14/skywhale.jpeg "Introducing Skywhale: Canberra, Australia’s Controversial $300K Centenary Balloon [PHOTOS]")
![Meet Ahmed Angel: The Greatest Internet Superstar. Ever. [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/14/ahmed-angel.jpg "Meet Ahmed Angel: The Greatest Internet Superstar. Ever. [PHOTOS]")
![Airbus Shows Off The First A350 XWB, The Boeing 787's Rival [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/13/a350.jpg "Airbus Shows Off The First A350 XWB, The Boeing 787's Rival [PHOTOS]")
![Lisalla Montenegro: Meet Angels Pitcher C.J. Wilson’s New Supermodel Fiancé [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/10/lisalla-montenegro_3.jpg "Lisalla Montenegro: Meet Angels Pitcher C.J. Wilson’s New Supermodel Fiancé [PHOTOS]")
![Surviving Sandy: The Rockaways Rise From The Ashes Six Months Later [PHOTOS]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/09/breezy-point_4.JPG "Surviving Sandy: The Rockaways Rise From The Ashes Six Months Later [PHOTOS]")
![Swallowed By Hippo: Paul Templer, River Guide, Attacked By Hippopotamus On Africa's Zambezi River [VIDEO]](http://s1.ibtimes.com/sites/www.ibtimes.com/files/styles/v2_medium/public/2013/05/09/hippo.jpg "Swallowed By Hippo: Paul Templer, River Guide, Attacked By Hippopotamus On Africa's Zambezi River [VIDEO]")
Like or Follow us for updates on the biggest stories!